The Clinical Observation On The Treatment Of Chronic And Hard-to-heal Wounds With The Method Of "Simmered Pus And Long Meat" To Guide The Dressing Change Of Puffball Spore Powder

Objective:To observe the clinical efficacy and safety of "simmered pus and long meat" method and puffball spore powder in treating chronic and difficult-to-heal wounds.Methods:The experimental study selected total 50 patients who suffer from chronic and difficult-to-heal wounds were selected from January 2020 to December 2020 in the Department of orthopedics and traumatology of Jiangsu Provincial Hospital of traditional Chinese medicine.Two patients with similar wound types and basic conditions were paired into the group at the same time,and two patients were randomly assigned to the control group and the trial group,with 25 cases each in the control group and the trial group.The control group was treated with conventional dressing change of Western medicine,and the experimental group was treated with puffball spore powder.The treatment cycle was 4 weeks,there is no local external medicine for healing during treatment.Before treatment,1 week,2 weeks,3 weeks and 4 weeks after treatment,the patients were evaluated with Bates-Jensen Wound Assessment Tool(BWAT),wound re-epithelization score(bwat-1),wound exudation score(bwat-2),Visual Analogue Scale(VAS)and positive rate of bacterial culture.Results:Total 50 patients suffer from chronic hard-to-heal wounds were included in this study.There was no significant difference in personal baseline data including gender,age,course of disease,wound site,bacterial culturebwat score,BWAT scores and VAS score between the two groups,the two groups were comparable before treatment(P>0.05).Comparison of bwat scores between the two groups:there was no difference in bwat scores between the two groups after 1 week of treatment(P>0.05),but there was significant difference in bwat scores between the two groups after 2 weeks of treatment(P<0.05).Comparison of wound re epithelization score and bwat-1 score:there was significant difference in bwat-1 score between the two groups after 1 week of treatment(P<0.05).Comparison of bwat-2 score of wound exudation:there was significant difference in bwat-2 score between the two groups after 1 week of treatment(P<0.05).After 4 weeks of treatment,there was no statistical difference in VAS score change before and after drug exchange for two groups of patients(P>0.05),F tests with repeated measurement of technical data variance analysis were used before and after single group of VAS scoring therapy,and the VAS score of two groups of patients showed a downward trend,which was of significant statistical significance(P<0.05)Comparison of bacterial culture positive rate before and after treatment:after 2 weeks of treatment and 4 weeks of treatment,there was no significant difference in bacterial culture positive rate between the two groups(P>0.05).Comparison of curative effect between the two groups:after 2 weeks of treatment,there was no significant difference in the effective rate between the two groups(P>0.05).After 4 weeks of treatment,the effective rate of the experimental group was 64%,which was significantly higher than 40%of the control group,with statistical difference(P<0.05)Conclusion:Compared with the conventional dressing change of Western medicine,the method of"simmer pus and grow meat"and puffball spore powder can better improve the local state of chronic refractory wounds,effectively accelerate wound healing,promote wound epithelization and control wound exudation,control wound infection and reduce wound pain,which is worthy of clinical promotion and popularization.However,the clinical application,such as dosage form and administration mode,need to be further improved and studied,and the pharmacological effects of puffball.