Effects Of Early Life Stress And Mental Resilience On Psychiatric Health Outcomes

Objective: Early life stress is very common in human beings.Early stress is a risk factor for psychiatric health outcomes,and the occurrence of early stress has a wide and profound impact on individual psychological development.Mental resilience,as a factor to protect individuals,is closely related to the physical and mental health and happiness of individuals.Therefore,in order to take more targeted interventions for high-risk groups,and to provide theoretical basis for preventing or reducing adverse psychiatric health outcomes,this study explored the effects of early life stress and mental resilience on psychiatric health outcomes.Methods: Volunteers were recruited in Shenzhen and Changsha,including 239 healthy volunteers and 387 psychiatric disorder volunteers.Social demographic data and clinical data were collected by using telephone,We Chat,QQ and E-mail.The study measured general demographic data,early life stress,mental resilience,and psychiatric health outcomes,including groups using The psychosocial stress survey for groups(PSSG)and childhood trauma questionnaire(CTQ),ConnorDavidson Resilience Scale,DSM-5-Level 1 Cross-Cutting Symptom Measure(DSM5-L1CCSM),Self-rating depression scale(SDS),World Health Organization Disability Assessment Schedule 2(WHODAS2.0).Through SPSS21.0 software,t-test,partial correlation analysis,regression analysis and other methods were used to analyze before and after psychiatric health outcomes,the relationship between childhood and adult stress and mental resilience,as well as the interaction between childhood and adult stress matching on psychiatric health outcomes.Results:1.There were statistical differences in other data except gender,marriage,religious belief and sexual abuse between the psychiatric disorder group and the healthy volunteer group(P < 0.05).2.Childhood trauma questionnaire(CTQ)of CTQ total score,emotional abuse and emotional neglect and mental resilience scale between tenacity,strength and optimism are statistical significance(p < 0.01),the physical neglect and mental resilience scale between strength and optimism,also statistical significance(P < 0.01).There was a significant correlation between the factors of PSSG life stress and the factors of mental resilience(P < 0.01).3.Affective neglect factor in the childhood trauma questionnaire,strength and optimism factor in the mental resilience scale,and childhoodadult stress matching had statistically significant predictive effects on the total score of the first-grade symptom scale(P < 0.01).4.The predictive effects of physical neglect factor,all factors of mental resilience and matching variables of childhood stress in childhood trauma were statistically significant(P < 0.01),and the predictive effects of physical abuse factor were statistically significant(P < 0.05).5.Years of education,physical neglect factor of childhood trauma,strength and optimism factor of mental resilience,and the matching variable of childhood to adult stress had significant predictive effects(P <0.01),and the number of life stress events in the last 5 years had significant predictive effects(P < 0.05).Conclusion:1.Early life stress may significantly increase the risk of negative psychiatric health outcomes,and mental resilience may have an important protective effect on psychiatric health outcomes.Adulthood stress has no obvious effect on psychiatric health outcomes,but repeated exposure to the same type of stress as childhood stress in adulthood may significantly worsen psychiatric health outcomes.2.Early life stress may have a facilitation effect on adulthood stress,and mental resilience may mediate the facilitation effect of early life stress on adulthood stress.3.Early life stress may have inhibitive effects on the development of mental resilience,and children-adult stress matching may play a mediating role between early life stress and mental resilience.4.Emotional neglect and physical neglect in early life stress were the main risk factors for psychiatric health outcomes,while strength and optimism were the main protective factors for psychiatric health outcomes in mental resilience.