Anxiety,Depression And Insomnia Symptoms And Their Relevant Factors Among Newly-diagnosed Cancer Patients Of A Hospital In Guangzhou City

Objective This study aims to investigate newly-diagnosed cancer patient’s anxiety,depression and insomnia symptoms and its related influencing factors.Methods This is a retrospective,cross-sectional study.A total of 571 newly diagnosed cancer patients,with 52(9.1%)males and 519(90.9%)females(mean age:47.5±11.4,ranged from 21 to 88 years)were recruited from Guangdong Provincial People’s Hospital.All participants were requested to complete the Patient Health Questionnaire(PHQ9),and the General Anxiety Disorder(GAD7),and a psychiatrist was involved to assess patient’s insomnia symptoms.Sociodemographic,clinical and psychosocial data were also collected.Multiple logistic regression analyses were conducted to examine the association between tested factors and the development of anxiety,depressive and insomnia symptoms.Results The prevalence of anxiety and depression symptom of this sample was 28.2%(161/571),and 35.0%(200/571)respectively,and the rate of insomnia was 89.0%(508/571),Multiple logistic regression showed that older age(greater than 60 years,OR=2.639,95%CI:1.105～6.306,P=0.029),unemployment(OR=2.016,95%CI:1.046～3.884,P=0.036),physical comorbidity(OR=1.742,95%CI:0.377～0.870,P=0.010),higher life stress level(OR=2.691,95%CI:1.157～6.259,P=0.022),and negative personality(OR=6.438,95%CI:3.641～9.904,P<0.001)were significant independent risk factors for depressive symptom.Married status(OR=0.175,95%CI:0.070～0.437,P<0.001),living with friends(OR=0.082,95%CI:0.014～0.492,P=0.006)and families(OR=0.247,95%CI:0.062～0.983,P=0.047)were significant protective factors for depression among cancer patients.Positive family cancer history(OR=1.719,95%CI:1.085～2.723,P=0.021),high level of stress(OR=6.777,95%CI:2.902～15.826,P<0.001),and negative personality(OR=4.384,95%CI:2.706～7.102,P<0.001)were significant risk factors for anxiety symptom.Married status(OR=0.415,95%CI:0.181～0.954,P=0.038)was the protective factor for anxiety symptom.Low income level(month income 3000 to 5000,OR=3.252,95%CI:1.221～8.663,P=0.018),living with families(OR=8.604,95%CI:1.921～38.528,P=0.005),having had radiotherapy(OR=3.356,95%CI:1.358～8.295,P=0.009)and chemotherapy(OR=2.447,95%CI:1.023～5.852,P=0.044)were significant risk factors for insomnia symptoms.Conclusion Anxiety,depression and insomnia symptoms were more often to be seen in newly-diagnosed cancer patients than the ordinary population.Health professionals should focus more on patient’s mental health while providing routine anti-oncology treatment.Increased attention should be given to those who are older,unemployed,having high stress level,living alone,single,and those with negative personality,having been through radiotherapy and chemotherapy.More family and social support are needed to help with the patient’s recovery as well as improving the individual’s quality of life.