Analysis Of Risk Factors Related To Hypocalcemia In 122 Neonates

Purpose Through retrospective study,we collected the clinical data of 122 cases of hypocalcemia in neonatal ward of our hospital,analyzed the related risk factors of neonatal hypocalcemia,understood the correlation between clinical symptoms of hypocalcemia and blood calcium concentration,and further understood the complications of neonatal hypocalcemia,At the same time,it is expected to reduce the incidence of neonatal hypocalcemia and improve the prognosis.Methods 341 cases of children who met the inclusion criteria from July 2017 to June2020 in the neonatal ward of our hospital were collected.The specific data included the general situation of the children and the situation of the mother during pregnancy.According to the concentration of serum calcium in venous blood,they were divided into neonatal hypocalcemia group(122 cases)and non neonatal hypocalcemia group(219 cases).The related risk factors of neonatal hypocalcemia were analyzed retrospectively.Whether there was hypocalcemia as a dependent variable,the risk factors of the occurrence of neonatal hypocalcemia as independent variables,and spss25.0 statistical software was used to analyze the data,P The statistical significance of high-risk factors were analyzed by multi factor analysis,and finally,the logistic regression model was established to analyze the non conditional multi factor Logistic regression.Results 1.The lower the birth weight,the younger the gestational age and the lower the Apgar score within 5 minutes of birth,the higher the incidence of hypocalcemia in newborns.2.In the neonatal hypocalcemia group,115 cases(94.27%)had early-onset neonatal hypocalcemia,and 7 cases(5.73%)had late-onset neonatal hypocalcemia.3.Analysis of related risk factors of neonatal hypocalcemia: birth weight,gestational age,Apgar score within 5 minutes of birth,intracranial hemorrhage,multiple fetuses,maternal pregnancy induced hypertension and gestational diabetes mellitus,a total of 7factors in neonatal hypocalcemia group and non neonatal hypocalcemia group were statistically significant(P < 0.05),which were related risk factors;multiple factors were statistically significant(P < 0.05)Unconditional logistic regression analysis showed that birth weight,gestational age,Apgar score within 5 minutes of birth,multiple fetuses,maternal pregnancy induced hypertension and gestational diabetes mellitus were independent risk factors for neonatal hypocalcemia,which were more likely to lead to neonatal hypocalcemia.4.There were 24 cases of clinical symptoms and signs in neonatal hypocalcemia group.T-test analysis showed that there was no significant difference between serum calcium concentration and clinical symptoms(P > 0.05),so there was no significant correlation between serum calcium concentration and clinical symptoms and signs in neonatal hypocalcemia.Conclusion 1.According to the results of this study,early-onset neonatal hypocalcemia is more common than late-onset neonatal hypocalcemia.2.The lower the birth weight,the younger the gestational age,the lower the Apgar score within 5 minutes of birth,and the mother’s gestational diabetes or hypertension,the more likely the newborn to have hypocalcemia.3.There is no significant relationship between the clinical symptoms and signs of neonatal hypocalcemia and the blood calcium concentration.