Evaluation Of Yi Shen Tong Luo Recipe In The Treatment Of Type Ⅲ Prostatitis (Kidney Deficiency And Collateral Blockage Syndrome)

Objective:To observe the efficacy and safety of Yi Shen Tong Luo Decoction in the treatment of type Ⅲ prostatitis（Kidney Deficiency and Collateral Blockage Syndrome）,so as to provide new treatment ideas and prescriptions for clinical practice.Methods:The 120 patients were enrolled in the male outpatient department of Henan Province Hospital of Traditional Chinese Medicine（Second Affiliated Hospital of Henan University of Traditional Chinese Medicine）,the first affiliated hospital of Zhengzhou university and Zhengzhou hospital of traditional Chinese medicine from February 2018 to December 2018.They were randomly divided into treatment group and control group with 60 cases in each group.Treatment:The treatment group was treated with basic therapy combined with Yi Shen Tong Luo recipe,one dose a day,200ml each time,two warm doses in the morning and evening;Basic therapy:ⅢA type anterior adenitis oral levofloxacin lactate tablets,ⅢB type oral tamsulosin hydrochloride capsules;The control group only used basic treatment.After 4 weeks of treatment,observation compared two groups before and after treatment of TCM syndrome integral,chronic lead inflammatory integral index（NIH-CPSI）,prostate fluid Lecithin body（Lec）and White blood cells（WBC）change,to evaluate its efficacy and safety.Result:（1）In the treatment group,60 patients,4 patients fell off,6 were cured,23were markedly effective,16 were effective,11 were ineffective,and the total effective rate was 80.36%.There were 60 cases in the control group,4 cases were shedding,2cases were cured,17 cases were markedly effective,15 cases were effective,and 22cases were ineffective.The total effective rate is 60.71%.The treatment group was better than the control group P<0.05（the efficacy was compared with P=0.014,and the total effective rate was compared with P=0.023）.（2）Comparison of TCM symptom scores between the two groups:comparison between the two groups before treatment:P=0.319,no difference between the two groups,which was comparable.After treatment,the comparison between the two groups was P<0.05（note:P₁=0.000,P₂=0.000）,which was lower than that before treatment.After treatment,P=0.001,the difference between before and after treatment P=0.004,the treatment group is better than the control group.（3）Two groups of NIH-CPSI pain score comparison:before treatment,two groups of comparison P=1.0,no difference between the two groups,comparable.After treatment,the contrast between the two groups was P<0.05（Note:P₁=0.000,P₂=0.000）,which was improved than that before treatment.After treatment,the contrast was P=0.000,and the treatment group was superior to the control group.（4）Two groups of NIH-CPSI urinary symptoms score comparison:before treatment,the two groups compared P=0.906,the two groups had no difference,comparability;after treatment,the two groups were compared P<0.05（Note:P₁=0.000,P₂=0.000）,Compared with before treatment,there is a decrease.After treatment,P=0.883 was compared,although the urinary symptom scores were all decreased,but there was no difference between the two groups.（5）Two groups of NIH-CPSI quality of life score comparison:before treatment,two groups of comparison P=0.522,two groups have no difference,which comparability.After treatment,the two groups were treated with P<0.05（Note:P₁=0.000,P₂=0.000）,which was improved compared with before treatment.After treatment,the contrast was P=0.000,and the treatment group was superior to the control group.（6）Two groups of NIH-CPSI total score comparison:before treatment,two groups of comparison P=0.772,two groups have no difference,which was comparable.After treatment,the two groups were treated with P<0.05（Note:P₁=0.000,P₂=0.000）,which was improved compared with before treatment.After treatment,the contrast was P=0.000,and the treatment group was superior to the control group.（7）Two groups of prostatic fluid lecithin bodies and white blood cells comparison:before treatment,there is no difference between the two groups of patients,with comparability.After treatment,with statistical significance,P<0.05,in improving lecithin corpuscles,the treatment group was better than the control group;in improving white blood cells,P>0.05,without statistical significance,no significant difference.Conclusion:Yi Shen Tong Luo can significantly improve TCM symptoms score,NIH-CPSI pain score,NIH-CPSI quality of life score,and NIH-CPSI total score,which can improve pain symptoms and improve quality of life.For type Ⅲ prostatitis,from the viewpoint of"kidney deficiency and collateral obstruction",the treatment of Yi Shen Tong Luo Recipe is effective and safe,and can be popularized in clinical practice.