A Preliminary Study On The Clinical Diagnosis And Treatment Processes And Therapeutic Effects Of Underactive Bladder

Objective: To investigate the clinical diagnosis and treatment processes and therapeutic effects of underactive bladder.Methods: From July 2019 to January 2020,patients were collected from the urology department of Wuhan Union hospital.The clinical manifestations were frequent urination,urgent urination,dysuria,urination dribbling,lower abdominal distension and urinary retention.Urinary calculi,urethral stricture,urinary tract tumors,urinary tract infections,bladder outlet obstruction,benign prostatic hyperplasia,etc.were excluded.26 patients were diagnosed with UAB by detailed medical history,physical examination,neurological examination,urinary routine,urological ultrasound,cystography,urography and urodynamics,and 21 were followed up.A series of non-invasive comprehensive treatments include "continuous open catheterization,oral administration of drugs,instruction of patient urination training,and clean intermittent catheterization".Average daily micturition numbers,average volume of urine output per time,post-voiding residual,and KHQ-HR QOL scores before and after treatments were recorded to compare the improvement of symptoms and changes in quality of life of patients.Results: Among the 21 patients,5 were males,aged(54±9)years,and16 were females,aged(48±15)years.Before and after the treatments,the average volume of urine output per time,from(34.10±28.42)ml to(64.05±44.25)ml,was significantly increased(p<0.05),and the post-voiding residual,from(233.90±110.78)ml to(67.10±62.30)ml,was significantly reduced(p<0.05).In KHQ-HR QOL questionnaires,six aspects of General Health Perceptions(GHP),Severity of Urination Problems(SUP),Role Limitations(RL),Personal Relationships(PR),Emotions(EMO)and Sleep/Energy(S/E)significantly improved compared with those before treatments(p<0.05).Average daily micturition numbers before and after treatments had no significant difference(p>0.05).In questionnaire three aspects of Social Limited(SL),Physical Limitations(PL)and Severity Measure(CM)had no significant difference compared with those before treatments(p>0.05).Conclusions: After a series of noninvasive comprehensive treatments,the average volume of urine output per time increased and post-voiding residual urine volume decreased in patients diagnosed with underactive bladder.In addition,six aspects of General Health Perceptions(GHP),Severity of Urination Problems(SUP),Role Limitations(RL),Personal Relationships(PR),Emotions(EMO)and Sleep/Energy(S/E)in the KHQ-HR QOL questionnaire were significantly improved before and after treatments(p<0.05).During the process of treatments,clinical workers need to take personalized treatment measures for each patient.