Analysis Of 25 Hydroxyvitamin D Levels And Risk Factors In Patients With Myofascial Pain Syndrome

Objective:To investigate the serum level of 25 hydroxyvitamin D in patients with myofascial pain syndrome(MPS),and to explore the possible correlation between the two and the risk factors for myofascial pain syndrome.Methods:In pain clinic collected 85 cases of patients diagnosed with myofascial pain syndrome as the experimental group,85 cases collected in our hospital medical health check-up,as healthy control group,two groups of age,gender,weight,height,living environment,outdoor sports,smoking,drinking and other general information,history of visits in the outpatient service clinical laboratory in pursuance of that day,25 hydroxyl vitamin D(25-(OH)D),erythrocyte sedimentation rate(ESR),parathyroid hormone(PTH),serum phosphorus,C-reactive protein(CRP),serum calcium were detected.Patients in the case group needed to record the course of disease,improve visual pain score(VAS)and health survey brief scale score(SF-36).After data detection and collection,the patients were divided into 4 groups according to 25-(OH)D level<25.00nmol/L as the severe deficiency group.25.00-49.99nmol/L was the deficient group,50.00-74.99nmol/L was the deficient group,and ≥75.00nmol/L was the normal group.The data were analyzed.Results:The mean level of 25-(OH)D in both healthy and MPS patients was lower than the normal level,but the mean level of 25-(OH)D in MPS patients was significantly lower than that in MPS patients(P<0.05).Compared among the 4 groups of MPS patients,the course of disease in the severe deficiency group was significantly longer than that in the insufficient and normal groups,while the course of disease in the deficiency group was significantly longer than that in the normal group(P<0.05).ESR and VAS of the severe deficiency group were significantly higher than those of the other three groups(P<0.05).The SF-36 scores of the severe deficiency group and the deficiency group were significantly lower than that of the insufficient group and the normal group(P<0.05).VAS score was negatively correlated with 25-(OH)D level(P<0.01).Multivariate Logistic regression analysis showed that female,overweight/obesity,humid environment,daily outdoor activity time <30 minutes and low 25-(OH)D were independent influencing factors for MPS(P<0.05).Conclusion:25-(OH)D is associated with MPS,and active intervention of related risk factors should be conducted in early stage to prevent or reduce clinical symptoms and delay disease progression.