Investigation of the molecular and physiologic properties of calpain and its role in G1 to S phase transition

he Ca;It has been proposed that calpain is activated by an autoproteolytic mechanism. If this is true, one would expect a relatively short half-life for calpain protein in cells. To test this hypothesis, several human cell lines were pulse-labeled with ;The effect of a calpain specific cell permeant inhibitor, ZLLY-CHN;Overexpression of active...