| The use of matrix assisted laser desorption/ionization (MALDI) mass spectrometry has been a valuable analytical technique for the analysis of biological samples and synthetic polymers.[1] MALDI mass spectrometry provides good sensitivity with a detection limit of about femtomole concentrations depending on the molecular weight of the sample analyzed. It has the advantage of applying simple sample preparation methods. However, the success of a MALDI experiment for a given analyte is highly dependent on the kind of matrix applied. [2] Here, the use of room temperature ionic liquids was investigated as matrices for Fourier transform mass spectrometry (FTMS). |
