| ObjectiveTo explore the clinical efficacy and safety of acupuncture in the treatment of benign prostatic hyperplasia(BPH)based on "Yi-shen shu-gan Li-qi shu-ji" method,and to explore the efficacy and safety of acupuncture in the treatment of benign prostatic hyperplasia(BPH)reported in modern literature.MethodsIn the part of the research,we use the Cochrane Library database,the PubMed database,the full-text database of Chinese academic journals(CNKI),(full-text version),the Wanfang database,From 2004 to 2018,modern literatures on acupuncture treatment of benign prostatic hyperplasia(BPH)were collected from 2004 to 2018,and the full text was searched and analyzed.The literature that we included in the study had a more rigorous clinical randomized controlled trial study scheme,and applied the bias risk of Cochrane The measurement tool carries on the risk quality analysis to each document.We then use the Review Manager(Version5.3)statistical software provided by the website to analyze and study the literature that meets the inclusion criteria and does not meet the exclusion criteria.In the second part of the study,the sample size was collected according to the most simple exploratory clinical control test,because there was no reference in the literature report with completely consistent test methods.So we selected 67 patients from September 2016 to February 2019 in the acupuncture department of Fengtai traditional Chinese Medicine Hospital in Beijing and Changxindian Town Community Health Service Center from September 2016 to February 2019 according to the requirements of inclusion criteria and exclusion criteria,and divided them into test group(33 cases)and control group(34 cases).The experimental group was treated with acupuncture medium pole,Taichong,Taixi,Sanyinjiao point combined with western medicine Tansoroxine sustained-release capsule,while the western medicine group was treated with Tansuloxine sustained-release capsule The course of treatment in both groups was 1 month.Before and after treatment,the patients’ international prostate symptom score(IPSS),quality of life index(QOL)was recorded at three time points during the follow-up.,nocturnal urine times,urine thread status,abdominal symptoms,maximum urine flow,residual urine volume integral,prostate volume under ultrasound,and so on.Spssl 18.0 statistical software was used to analyze the data.ResultsA total of 16 randomized trial literatures were obtained,involving 1620 patients Acupuncture combined with routine treatment can improve the total effective rate of patients after treatment,the international prostate symptom score,reduce the residual urine volume of the patient’s bladder,reduce the volume of the patient’s prostate,increase the urine flow of the patient,etc.(P<0.05),but there was no difference between the test group and the control group for the quality of life QOL score,urination waiting time(s)and so on(P>0.05)The second part,overall curative effect:experimental group of acupuncture combined with western medicine to improve the symptoms and signs of patients overall curative effect(86.67%)is better than the control group(74%)(P<0.05).The improvement of international prostate symptom score(IPSS):after treatment,the international prostate symptom score(IPSS)of the two groups was significantly improved(P<0.01),and that of each group before and after treatment and during the follow-up period was significantly improved(P<0.05).The improvement of scores after treatment and follow-up in the experimental group was better than that in the control medicine group(P<0.01).Improvement in quality of life(QOL)scores:after treatment,two The quality of life(QOL)scores of the patients in the group were significantly improved(P<0.01),and the scores before and after treatment and during the follow-up period were significantly improved in each group(P<0.05).The scores of the experimental group and the follow-up group were better than those of the control group(P<0.01).Improvement of nocturnal urine scores:after treatment,the scores of nocturnal urine times in the two groups were significantly improved(P<0.01),and the scores before and after treatment and during the follow-up period were significantly improved in each group(P<0.05).The improvement of nocturia frequency after treatment and follow-up in the experimental group was better than that in the control group(P<0.01).Improvement of urinary line score:after treatment,the two groups of patients The score of urinary line was improved significantly in each group before and after treatment and during the follow-up period(P<0.01).After treatment and follow-up,the improvement of the experimental group was better than that of the control group,but there was no significant difference between the two groups(P>0.05).Improvement of abdominal symptom score:after treatment,the abdominal symptom score of the two groups was improved obviously,and there was significant improvement before and after treatment and during the follow-up period(P<0.01).The improvement of index during follow-up period in experimental group was better than that in control group(P<0.01),but the improvement of small abdomen score between the two groups after treatment was statistically significant(P>0.05).)The improvement of the score of maximal urine flow rate:after treatment,the score of maximal urine flow rate of the two groups was improved obviously,and the comparison before and after treatment and during the follow-up period of each group had obvious improvement(P<0.01).The improvement of experimental group and follow-up period was better than that of control group(P<0.01).The improvement of residual urine volume(ml):after treatment,the residual urine volume of the two groups was significantly improved(P<0.01),and there was significant improvement before and after treatment and during the follow-up period of each group(P<0.05).The improvement results after treatment and follow-up in the experimental group were better than those in the control group(P<0.05).Residual urine volume The change of scores:after treatment,the residual urine volume of the two groups was improved significantly,and there was significant improvement before and after treatment and during the follow-up period(P<0.01).There was no significant difference between experimental group and control group after treatment(P>0.05).However,the results of follow-up in the experimental group were better than those in the control group(P<0.01).Improvement of prostate volume(V):there was no significant difference in prostate volume between the two groups after treatment and during follow-up(P>0.05).The results of post-treatment and follow-up showed that the volume of prostate in the experimental group was slightly smaller than that in the control group,but there was no statistical difference.Difference(P>0.05)Removal and treatment:There were 7 cases of abscission,including 3 cases in test group and 4 cases in control group.Because the abscission case data fell off before the end of the trial,the data of the study was incomplete(no post-trial and follow-up data),so we did not included in the analysis.ConclusionIn this study,the efficacy of acupuncture in the treatment of benign prostatic hyperplasia(BPH)was studied by systematically evaluating the therapeutic effect of TCM literature on benign prostatic hyperplasia(BPH).The results show that acupuncture treatment of benign prostatic hyperplasia has a relatively stable curative effect,but the literature is still mainly individual,small samples,low quality,still lack of clinical multicenter,large samples,and high-quality randomized controlled trial research literature,this is the direction that still needs to be worked out in the future.The results of clinical trial showed that acupuncture at middle pole,Taichong,Taixi and Sanyinjiao points combined with western medicine Tansoroxine sustained-release capsule in improving the overall curative effect,improving the prostate symptom score(IPSS),quality of life index(QOL),nocturnal urine times,urine thread status,There were obvious differences in evaluation of symptoms of small abdomen,maximal urine flow and residual urine volume,which highlighted the advantage of acupuncture in the treatment of benign prostatic hyperplasia(BPH)by "Yi-shen shu-gan Li-qi shu-ji". |
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