Clinical Observation Of Tongmai Decoction In The Treatment Of Stable Angina Pectoris Of Qi Deficiency And Blood Stasis

Objective: By observe the clinical efficacy and safety of Tongmai decoction in the treatment of qi-deficiency and blood-stasis stable angina pectoris,so as to provide reference for the treatment of CHD.Methods:In 60 cases of qi deficiency and blood stasis in patients with stable angina,were randomly divided into control group(western medicine foundation treatment),Tongmai decoction group(Tongmai decoction and western medicine foundation treatment),with 30 cases each,and 4 weeks treatment,then analysis the TCM syndrome efficacy of two groups of patients before and after treatment,angina symptom curative effect,therapeutic electrocardiogram curative effect,life quality and routine blood fat,the change of c-reactive protein.Results:Before treatment,there was no statistical difference in the distribution of gender,age,onset time,previous medical history,personal adverse habits,angina pectoris CCS level,angina pectoris symptom severity,etc.(1)In terms of improving the efficacy of TCM symptoms,the total effective rate was 83.3% in Tongmai decoction group and 63.3% in the control group,with statistically significant differences(P=0.036).(2)In terms of the efficacy of improving the symptoms of angina pectoris,the total effective rate was 80% in Tongmai decoction group and 56.7% in the control group,with statistically significant differences(P=0.042).(3)In terms of the efficacy of quality of life evaluated by the quality of life system-coronary heart disease scale in patients with chronic diseases,compared with the control group before and after treatment,Tongmai decoction group can improve the quality of life,and is better than the control group,the difference is statistically significant(P<0.05).(4)Tongmai decoction group could effectively reduce the levels of c-reactive protein,total cholesterol in blood lipids and low-density lipoprotein,and the differences were statistically significant before and after treatment and compared with the control group(P<0.05).(5)In terms of electrocardiogram efficacy and improvement of triglyceride and HDL levels in blood lipid,Tongmai decoction group and control group had certain effects,but the difference was not statistically significant(P>0.05).Conclusion:Tongmai decoction can effectively improve the TCM symptoms,angina symptoms,quality of life and significantly reduce the levels of c-reactive protein,total cholesterol and LDL in the blood of patients with stable angina pectoris due to qi-deficiency and blood stasis.