Based On 1640 Cases Of Cognitive Impairment, The Cognitive, TCM Physical Characteristics And Influencing Factors Of Vascular Dementia Were Analyzed

Vascular dementia(VD)is one of the main types of dementia.It occurs after various cerebrovascular diseases,which seriously threatens the health of the elderly.In the theory of traditional Chinese medicine in ancient China,vascular dementia mainly belongs to the category of "dementia","forgetfulness".TCM constitution is a comprehensive and relatively stable intrinsic trait of human body in terms of innate and acquired morphological structure,physiological function and psychological state,which is related to disease.VD,as a preventable type of dementia,is associated with a variety of influence factors,whose connection with TCM constitution is still unclear.Based on this,the study carries out epidemiological investigations with characteristics of traditional Chinese medicine,and conducts research on the identification of vascular dementia and related influence factors,to provide evidence for early prevention and treatment,which has great clinical significance.Objective:This study preliminary explores the influence factors of VD and the physical and psychological characteristics of vascular dementia patients.As a supplement,we want to seek a sufficient theoretical basis for the development of the diagnosis and treatment model of vascular dementia and the treatment path of TCM constitution regulation,and provides a new idea for the prevention and treatment of vascular dementia patients.Methods:1.ParticipantsIndividuals were recruited from the Jing Zhuang Community Health Service Center,Shen Jiaying Community Health Service Center,Xiangshan Street,Hai Dian District Hot Spring Community Health Service Center,Xiyuan Hospital Outpatient Department and Inpatient Department,form June 2018 to November 2018.2.Investigation methodsThe cross-sectional survey method of convenient sampling was adopted,and the survey was conducted in the form of questionnaires.A total of 2056 people aged 45-85 were selected for questionnaires.The questionnaire consists of the following parts:1.General information;2.Medical history;3.Physical constitution of traditional Chinese medicine;4.Emotional questionnaire;4.Dietary questionnaire;and 5.Neuropsychological scale.All subjects were divided into VD group,AD group,MCI group,VCIND group and NCI group according to the diagnostic criteria.There were 1640 cases of cognitive impairment.Data from vascular dementia group was mainly studied and compared with other groups.The VD group was and compared with other groups.Data extracted form questionnaires was filled in Excel and analyzed by SPSS 22.0.Difference in categorical data was measured by the Chi-Square test or non-parametric and expressed as composition ratio or frequency distribution;Continuous data were expressed as x±s(mean±standard deviation).If it conforms to the normal distribution and has the same variance.The analysis of variance compares the data.If the data conform to normal distribution but the variance is uneven or non-normal distribution,the non-parametric test is used.Single factor and multifactor logistic regression analysis of VD and its influencing factors were performed using SAS 9.2 software,and relevant conclusions were drawn.There was no significant difference in test level(a= 0.05,P>0.05),P<0.05 was significant difference.Results:1.The onset of vascular dementia was influenced by many factors,including old age,low education background,no family history of hypertension,history of hypertension,history of diabetes,history of heart disease,cerebrovascular disease,eating pickled food every day are the risk factors of VD.Brain work,holding the concept of health care of traditional Chinese medicine,eating fruit every day,balanced meat quality are the protective factors of VD.2.Compared with AD,MCI,VCIND and NCI groups,there were significant differences in sex and age distribution,family history of hypertension and diabetes,control of basic indicators such as diabetes,hypertension,cerebrovascular disease,heart disease,blood pressure and blood sugar,diet,daily life and emotions(P<0.05).There were no significant differences in marital status,BMI and other aspects between VD group and AD,MCI,VCIND and NCI group(P<0.05).VD group is generally elder,with the largest proportion of primary school education,92%of them engaged in manual labor,21.8%of them smoke and 22.7%drink,59.41%have abnormal BMI,26.38%,67.20%,50.46%and 23.85%have diabetes,hypertension,cerebrovascular disease and heart disease,respectively.Most of them have diet preference,unusual exercise and no health care concept of traditional Chinese medicine.Their main emotion is joy.3.The main TCM constitution types of VD patients were Yin deficiency for 109 cases(27.05%),Peacefulness for 61 cases(15.14%),Yang deficiency for 59 cases(14.64%),Qi deficiency for 58 cases(14.39%),Qi depression for 46 cases(11.41%),phlegm dampness for 36 cases(8.93%),blood stasis for 24 cases(5.96%),damp-heat for 6 cases(1.49%)and idiosyncrasy for 4 cases(0.99%).Among the combined constitutions of VD patients,Qi deficiency and Yin deficiency are the most common.The number of female VD patients with Yin deficiency,qi depression and yang deficiency constitution was significantly higher than that of male VD patients.There was no significant difference in physical fitness among VD education levels(P=0.14).The constitution of middle-aged group is the most peaceful,followed by Qi deficiency and Yang deficiency;the most constitution of old group is the Yin deficiency,followed by gentle and Yang deficiency;the constitution of old group is the largest proportion of Yin deficiency,followed by Qi deficiency and blood stasis.4.Compa red with AD,MCI,VCIND and NCI groups,the results of MMSE in VD group were lower than those in other groups in orientation,memory,attention and calculation,recall,language ability and the total score of MMSE(P<0.05).Compared with AD,MCI,VCIND and NCI groups,the results of MoCA scale in VD group were lower than those in AD group(P<0.05).The scores of other abilities in VD group were lower than those in AD group,but there was no significant difference(P>0.05).All abilities of VD group were lower than those of MCI,VCIND and NCI group,and the difference was statistically significant(P<0.05).5.The results of comparing the constitutional characteristics of different conditions between VD and AD showed that in the patients with severe dementia,the Yin deficiency,Qi depression and peace quality were more common in both groups,with no statistical difference(P=0.33);in the patients with moderate dementia,Yin deficiency,peace,Yang deficiency and phlegm dampness were more common in the two groups,with no statistical difference between the two groups(P=0.19);in the patients with mild dementia,Yin deficiency and Qi deficiency were more common in group VD than in group AD(P=0.02).Conclusion:1.Diabetes and other risk factors of vascular injury,old age,low education level,hypertension,eating a large number of cured foods are risk factors for VD,while mental work,health care in traditional Chinese medicine,eating fruits,buckwheat balance are protective factors for VD.2.Yin deficiency is the most common TCM constitution type in VD patients,followed bypeacefulness,Yang deficiency and Qi deficiency.The proportion of Qi depression,phlegm-dampness and blood stasis is relatively smallg,while the proportion of dampness,heat and characteristics is the least.Yin deficiency and Qi depression are the most common constitutions in patients with severe VD,while Yin deficiency is the main constitution in patients with mild to moderate VD.3.The orientation ability,memory,attention and calculation ability,recall ability and language ability of VD patients were lower than those of AD,MCI,VCIND and NCI patients.