| Objective:Under the guidance of Chinese and western basic theories,this study reviewed th e TCM syndrome types and DOB values of Hp related chronic gastritis patients,expl ored their distribution rules,and studied their correlation through statistical analysis.In order to assist clinical syndrome differentiation and medication with objective DOB v alue data and make up for the deficiency of objective indicators in the process of TC M syndrome differentiation and treatment of Hp related chronic gastritis.Methods:107 patients who were admitted to the department of gastroenterology,dongzhime n hospital of Beijing university of traditional Chinese medicine from February 2018 to January 2019 were collected and diagnosed as Hp related chronic gastritis and met the inclusion criteria.According to the 2017 consensus on TCM diagnosis and treatment o f chronic gastritis,the syndrome is divided into five main syndromes:syndrome ofdiffi dence between liver and stomach,syndrome of damp-heat of spleen and stomach,syn drome of weakness of spleen and stomach,syndrome of deficiency of stomach Yinand syndrome of obstruction of stomach collaterals.The general information,four-diagnosis information,syndrome differentiation and classification of all patients covering all con tents of medical cases were recorded into the database,and the DOB value and releva nt data were analyzed with spss22.0,so as to summarize the distribution law and stud y the correlation.Results:(1)A total of 107 Hp related chronic gastritis patients were collected in this pap er,including 36 male patients and 71 female patients,the ratio of male and female pa tients was 1:1.97,suggesting that female patients were more than male patients.(2)The average age was 42.33 14.464 years.With the increase of age,the inciden ce of hp-related chronic gastritis is on the rise,and the peak period is 30-39 years ol d,after which the incidence declines.The proportion of young people is more than ha If of the total population,which is significantly higher than that of middle-aged and e lderly people,with significant statistical significance(P<0.01).(3)Among 107 Hp related chronic gastritis patients,spicy food was the most,sig nificantly higher than that of the patients and each group;Those who liked drinking s trong tea were significantly lower than those who liked drinking strong tea and each group,and the results were significantly different(P<0.01).There was no significant difference in patients with hp-associated chronic gastritis(P>0.05).(4)The patient DOB value in the sample was the lowest of 4.1,the highest of 97.5,and the mean value was 27.131 19.2142.The mean DOB of male patients was 21.794 18.1938,and that of female patients was 29.837 19.2737.This study suggested th at the amount of Hp vector in female patients was higher than that in male patients,which was statistically significant(P<0.05).(5)There was no significant difference in DOB between the youth group and the elderly group(P>0.05).The DOB mean of the middle-aged group was statistically different from that of the two groups(all P<0.05).The mean DOB of the middle-a ged group was lower than that of the youth group and the elderly group,and the Hp vector quantity of the middle-aged group in this sample was lower than that of the youth group and the elderly group.(6)In the TCM syndromes of 107 patients with hp-related chronic gastritis,the p roportion of syndrome types is from high to low:syndrome of diffidence between live r and stomach(37.38%),syndrome of deficiency of stomach Yin(26.17%),syndrome of damp-heat of spleen and stomach(22.43%),syndrome of weakness of spleen and s tomach(22.43%),syndrome of obstruction of stomach collature-blood stasis(4.67%).T he results showed that there were significant differences among different TCM syndro mes in hp-related chronic gastritis patients(P<0.01).The syndrome of disharmony b etween liver and stomach is the most common in Hp-associated chronic gastritis.(7)No statistical difference in DOB between 107 Hp related chronic gastritis pati ents and chronic gastritis inflammation(P>0.05).The results of this study showed t hat Hp infection could lead to severe inflammation in chronic gastritis,but DOB valu ecould not reflect the inflammation in gastric mucosa.(8)The analysis showed that there was no correlation between the DOB value an d the severity of symptoms(P>0.05).Conclusion:In the sample population,the incidence of Hp-related chronic gastritis is mainly rel ated to sex,age and diet.The most common clinical syndrome differentiation is liver-stomach disharmony syndrome,followed by stomach yin deficiency syndrome and sple en-stomach dampness-heat syndrome.Among them,the DOB value of patients with liv er-stomach disharmony syndrome was less than 35,and the DOB value of spleen-stom ach dampness-heat syndrome was more than 35.The degree of inflammation of chroni c gastritis caused by Hp infection tends to be severe,but the DOB value can not refl ect the degree of inflammation of gastric mucosa. |
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