| Objective:To observe the prevention and treatment of adult chronic bronchial asthma by acupoint application,and to provide a clinical basis for the promotion and application of acupoint application.Methods:102 adult chronic bronchial asthma patients were divided into two groups:observation group(applied No.1 drug,referred to as drug application group)47 cases;control group(applied No.2 drug,referred to as micro-dose drug group)55 cases.The acupoints applied to the drug group were bilateral Feishu,Xinshu and Yushu;the micro-dose drug group took the points of bilateral Feishu,Xinshu and Yushu.All subjects received a microdose of the drug during the three-volt period of the first year.In the second year,the observation group was given a drug for application;the control group was given a micro-dose drug.From the first day of 2015,every 13 weeks,follow-up 4 times a year for 3 consecutive years,a total of 12 follow-up.Observed and recorded the number and severity of asthma attacks in patients before and after treatment,asthma control test(ACT)scale score,skin irritation intensity score,pulmonary function related indicators FEV1,FEV1/FVC,PEF dynamic changes and safety Evaluation,comprehensive comparison and analysis,can help to evaluate the clinical efficacy and safety of Sanfu paste in the prevention and treatment of adult chronic bronchial asthma.Result:1.The number and severity of asthma attacks;After 3 years of application,the number of acute episodes in the two groups decreased compared with that before the application,and the severity was reduced(p<0.05).Compared with the micro-dose group,the application group had fewer acute episodes per year(p<0.05)and less severe(p<0.05).2.Asthma Control Test(ACT)Scale: Compared with before the application,the ACT scores improved after the application of the two groups.Compared with themicro-dose group,the ACT score of the application group improved more significantly(p<0.05).3.Comparison of lung function: The comparison of FEV1,FEV1/FVC and PEF in the two groups before treatment,p>0.05,was comparable.In the first year of observation,compared with before treatment,FEV1/FVC and PEF were increased in the application group(p<0.05),and the FEV1 value was increased,but P>0.05,compared with the micro-dose group,FEV1,FEV1/FVC,PEF.Change,p>0.05.In the second year of observation,compared with the pre-treatment and micro-dose groups,the FEV1,FEV1/FVC and PEF in the application group were significantly increased(p<0.05).The value of the micro-dose group increased before and after treatment,but P>0.05.4.Correlation analysis between skin irritation intensity and clinical efficacy: There is a positive correlation between the degree of skin irritation and the difference between ACT,asthma attack frequency,lung function index(FEV1%,PEF L/S,FEV1/FVC%)before and after treatment..That is,the greater the degree of skin irritation,the greater the difference in clinical efficacy indicators,the more obvious the effect.5.Safety evaluation: There were no abnormalities in blood routine,urine routine,and chest X-ray before and after application in 47 patients in the application group.Only one case of severe skin itching,redness,edema and other allergic phenomena occurred during clinical observation.Affect the next application.No obvious toxicity or side effects were found,suggesting that the drug is safe for clinical application.Conclusion:1.During the three-volt period,acupoint sticking Feishu,Xinshu and Yushu can effectively improve the symptoms and severity of asthma attacks in adults with chronic bronchial asthma and improve the quality of life of patients.2.the acupoint application of skin stimulation intensity is stronger,the more obvious the symptoms of asthma improvement. |
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