| Objective: To describe objectively the characteristics of tongue and face diagnosis with different syndromes types in patients with type 2 diabetes mellitus,and to explore the correlation between characteristics of tongue and face diagnosis and laboratory indicators as well as the features of tongue and face parameters change before and after treatment.Methods:(1)The digital tongue and face-to-face diagnostic instrument(model: DKFII)independently developed by Shanghai University of Traditional Chinese Medicine was used to collect the information of tongue and face-to-face diagnosis in 320 patients with type 2 diabetes mellitus,and to collect the medical history data and related laboratory indicators of type 2 diabetes mellitus at the same time.(2)Statistical methods used oneway ANOVA to analyze the differences of hypoglossal and face-to-face diagnostic parameters of different syndromes in type 2 diabetes mellitus;canonical correlation analysis was used to explore the correlation between tongue and face-to-face diagnostic parameters and clinical biochemical indicators in type 2 diabetes mellitus patients;paired t test was used to observe the changes of tongue and face-to-face diagnostic information before and after treatment.Results:(1)Type 2 diabetes mellitus is characterized by asthenia in origin and asthenia in superficiality,and its pathogenesis mainly lies in yin fluid being insufficient,excess of dryness-heat,and deficiency of both qi and yin for basis,dryness-heat of phlegm and blood stasis as the standard.Among 320 patients with type 2 diabetes mellitus,deficiency of both qi and Yin and endoretention of damp heat syndrome are common.(2)There are some changes in tongue and face diagnostic parameters with different syndromes types in patients with type 2 diabetes mellitus.(1)Comparison of tongue complexion parameters with different syndromes types: compared with the deficiency of both yin and yang group,the R,G and B values of tongue complexion increased significantly in the extreme heat due to deficiency of yin group and the endoretention of damp heat group(P< 0.05),and the R values of tongue complexion in deficiency of both the qi and Yin group also increased significantly(P < 0.05);compared with the deficiency of both qi and Yin group,the R and B values of tongue complexion in the extreme heat due to deficiency of yin group increased significantly(P < 0.05),the R,G and B values of tongue complexion increased significantly in the endoretention of damp heat group(P < 0.05);Compared with the extreme heat due to deficiency of yin group,the G value of tongue complexion increased significantly in the endoretention of damp heat group(P < 0.05).(2)Comparison of the fur complexion parameters in different syndromes types: Compared with the deficiency of both yin and yang group and the deficiency of both qi and yin group,the R,G and B value of fur complexion increased significantly in the extreme heat due to deficiency of yin group and the endoretention of damp heat group(P < 0.05).(3)Comparison of facial complexion parameters in different syndromes types: Compared with the deficiency of both yin and yang group,the W value of facial complexion decreased significantly in the deficiency of both qi and yin,the extreme heat due to deficiency of yin group and the endoretention of damp heat group(P < 0.05),and the Y value of facial complexion increased significantly in the endoretention of damp heat group(P < 0.05);compared with the deficiency of both yin and yang group,the W value of facial complexion decreased significantly in the extreme heat due to deficiency of yin group and the endoretention of damp heat group(P < 0.05),and the Y value of facial complexion increased significantly in the endoretention of damp heat group(P < 0.05).Compared with the extreme heat due to deficiency of yin group,the Y value of the facial complexion increased significantly in the endoretention of damp heat group(P < 0.05).(4)Comparison of lip complexion parameters in different syndromes types: Compared with the extreme heat due to deficiency of yin group group,the S value of the lip complexion increased significantly in the deficiency of both yin and yang group and the deficiency of both qi and yin group(P < 0.05).(3)Analysis of the correlation between tongue and face diagnostic parameters and laboratory indexes in patients with type 2 diabetes mellitus.To some extent,tongue diagnostic parameters can predict the changes of laboratory indexes,of which a canonical correlation coefficient was 0.932.The R value of tongue complexion,putrefaction characteristic value and thickness characteristic value are most closely related to cholesterol,glycosylated hemoglobin and triglyceride,and the correlation coefficients were 0.849,0.781 and 0.770,and the correlation was positive.(2)The face diagnostic parameters could predict the changes of laboratory indexes to a certain extent,and the canonical correlation coefficient was 0.834.The correlation coefficients of facial Y value with blood sugar and glycosylated hemoglobin were 0.732 respectively,and they were positively correlated.(4)Comparison of tongue and face diagnostic parameters before and after treatment in patients with type 2 diabetes mellitus: There was significant difference in G value of fur complexion between the two groups before and after treatment(P < 0.05),and the G value of fur complexion in the treatment group was lower than that in the treatment group,and there was also significant difference in comparison of tongue puncture characteristics(P < 0.05),and the characteristic value of point puncture after treatment was lower than that before treatment.However,there was no significant difference in the face diagnostic parameters before and after treatment.Conclusion: 1.Type 2 diabetes mellitus is characterized by asthenia in origin and asthenia in superficiality,and its pathogenesis mainly lies in yin fluid being insufficient,excess of dryness-heat,and deficiency of both qi and yin for basis,dryness-heat of phlegm and blood stasis as the standard and they were mutually causal.Among 320 cases of type 2 diabetes in this study,the proportions of deficiency of both qi and yin and endoretention of damp heat were the most.2.DKF-II can objectively describe the characteristics of tongue and face diagnosis with different syndromes types in patients with type 2 diabetes mellitus.There are significant differences in tongue,the R,G and B values of face diagnostic parameters,thickness characteristic value,fat and thin characteristic value,the W and Y values of face complexion and face complexion index between different syndromes of diabetes mellitus,suggesting that tongue and face diagnostic parameters can be used as one of the objective basis of clinical differentiation of the disease.3.There is a certain correlation between tongue and face diagnostic parameters and clinical biochemical indicators in patients with type 2 diabetes mellitus,which indicates that tongue and face diagnostic parameters may become one of the characteristic indicators of traditional Chinese medicine for auxiliary clinical diagnosis and predicting disease prognosis.4.By observing the changes of tongue and facial complexion parameters before and after treatment in patients with type 2 diabetes mellitus,it is suggested that tongue complexion parameters can be used as one of the means to evaluate the curative effect of type 2 diabetes mellitus. |
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