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Study On Related Factors And TCM Syndromes Of Polyp Of Colorectal Adenoma

Posted on:2021-05-13Degree:MasterType:Thesis
Country:ChinaCandidate:L TianFull Text:PDF
GTID:2404330629983624Subject:Integrative Medicine
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Background:Intestinal polyp refers to various protruding,protruding intestinal cavity with protruding naked eye on the mucosal surface of the intestinal cavity.According to the study,the canceration rate of adenomatous polyps is about 1.4% to 20.4%,which is an important precancerous lesion of colorectal cancer~ [1],while epidemiological surveys show that nearly half of colorectal cancer is caused by the carcinogenesis of intestinal adenoma polyps,so the idea that colorectal adenoma polyps are the most common precancerous state of colorectal cancer is widely accepted.Recent studies have shown that the incidence and mortality of the disease in the Asian region is also on the rise,while with the economic development of our country,the national living standard and dietary structure and living rhythm have significantly changed,according to the 2017 Chinese colorectal cancer diagnosis and treatment norms,the incidence and mortality of colorectal cancer in China continues to rise.Currently,the medical community has a deeper understanding of the disease,but the treatment technique is relatively single.Nowadays,endoscopic polypectomy is the most widely used and mature technique,but the relapsing rate and malignant rate are still high,which makes the prevention of colorectal polyps more important.Methods:Through the inquiry of relevant literature and the summary of clinical experience,the risk factors of clinical symptoms of colorectal adenomatous polyps and the observation table of TCM syndromes were listed(Appendix 2).From January 2019 to December 2019 in Shanxi Provincial Hospital of Chinese Medicine(73 cases),Shanxi Provincial People’s Hospital(134 cases),Shanxi Provincial People’s Hospital(70 cases)and Affiliated Hospital of Shanxi College of Traditional Chinese Medicine(20 cases),a total of 297 routine enteroscopy and adenomatous polyps were confirmed as adenomatous polyps in Shanxi Provincial Hospital of Traditional Chinese Medicine(89 cases),Shanxi Provincial People’s Hospital(86 cases),Shanxi Provincial People’s Hospital(41 cases)and Affiliated Hospital of Shanxi College of Traditional Chinese Medicine(10 cases).At the same time,the clinical manifestations of the above 297 patients with adenomatous polyps were investigated,the symptoms,signs,tongue and pulse of traditional chinese medicine were analyzed,the frequency and frequency of each clinical symptom were counted,the data of the four diagnoses were analyzed by K-means cluster analysis,and the syndrome types of patients with tuberculous polyps were classified according to the clinical professional knowledge.Research results:1.Patients with colorectal adenomatous polyps were more male than female,and the risk of colorectal adenomatous polyps in women was 53% of that of men;2.The occurrence of colorectal adenomatous polyps,in a population already suffering from colorectal polyps,whether its pathological nature is adenomatous,is not significantly related to age;3.Family genetics increases the risk of colorectal adenomatous polyps;4.The incidence of adenomatous polyps was 2.264 times and 2.369 times as high as that of nonsmokers.;5.Fiber vegetable intake,according to the standard of 250 g/Day,the higher the intake of fiber vegetables,the higher the frequency of intake,the lower the risk of adenomatous polyps,the risk of disease is 32.7% of the population with insufficient intake;6.The risk of adenomatous polyps was 5.731 times that of regular diet;7.Eating shanxi aged vinegar is a protective factor for colorectal adenomatous polyps.the more aged polyps are eaten,the lower the incidence of adenomatous polyps is.occasionally,the incidence of adenomatous polyps is 42.9%,which is rare or not edible,and the proportion can be further reduced to 3.7%;8.Among the patients with adenomatous polyps in shanxi area,the number of cases of large intestine damp-heat syndrome is the most,the wet image is more important than the heat image;second,spleen deficiency and dampness accumulation syndrome,third,cold dampness block syndrome,fourth,Qi stagnation and dampness block syndrome,fifth,congestion and internal arrest syndrome,and a small number of patients without obvious clinical symptoms.Conclusions:1.More men than women with colorectal adenomatous polyps2.Whether the pathological properties of colorectal polyps were adenomatous was not significantly correlated with age.3.Familial inheritance increases the risk of colorectal adenomatous polyps.4.The incidence of colorectal adenomatous polyps in long-term smoking population was higher than that in non-smoking population.5.The lower the risk of colorectal adenomatous polyps with adequate fiber vegetable intake.6.Frequent hunger saturation and irregular diet increase the risk of colorectal adenomatous polyps.7.Eating Shanxi vinegar is a protective factor for colorectal adenomatous polyps.8.The syndrome type of colorectal adenomatous polyp in Shanxi area is the most.
Keywords/Search Tags:colorectal adenomatous polyps, related factors, case-control, logistic regression analysis, intestinal mushroom, TCM syndrome type, cluster analysis
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