Application Of Blood Gas Analysis In Labor Capacity Identification Of Pneumoconiosis

Objectives Through a comparative study of blood gas analysis（partial oxygen pressure）and lung function data of pneumoconiosis patients of different ages and periods,analyzed the correlation between partial oxygen pressure and lung function of pneumoconiosis patients,explored the reasonable oxygen partial pressure range in the disability identification of pneumoconiosis,which was to provide the scientific basis for the disability identification of pneumoconiosis.Methods These pneumoconiosis patients who were admitted to the Jingxi Occupational Disease Prevention and Treatment Hospital from January 2019 to December 2019 were selected as the research objects.The age,gender,pneumoconiosis stage,pulmonary function test results,and blood gas analysis test results were collected and evaluated.The patient’s hypoxemia and lung function damage were identified and the disability grade was identified.SPSS 24.0 statistical software package was used for data analysis,for such as analysis of variance,rank correlation,which were used to analyze the relationship between age,period,disability grade,partial oxygen pressure and lung function indicators.Partial correlation analysis and Kappa consistency test were used to analyze the relationship between oxygen partial pressure and pulmonary function.Based on the reference standard of pulmonary function injury,a new oxygen partial pressure classification interval was determined by ROC analysis,and then the oxygen partial pressure was re-classified.The Kappa test was used to determine the consistency between the new oxygen partial pressure grading interval and the impairment level of lung function identification.The chi-square test was used to evaluate the consistency rate between the old and new oxygen partial pressure grading intervals and the disability level of pulmonary function identification,and the value of the oxygen partial pressure grading interval.Results 1 A total of 391 pneumoconiosis patients were included in this study,all of whom were men.The age ranged from 51 to 94 years,with an average age of 69.24±7.44 years.303 cases of pneumoconiosis in stage Ⅰ（77.49%）,68 cases of pneumoconiosis in stage Ⅱ（17.39%）,and 20 cases of pneumoconiosis in stage Ⅲ（5.12%）.135 cases with normal blood gas（34.53%）,219 cases with mild hypoxemia（56.01%）,32 cases with moderate hypoxemia（8.18%）,and 5 cases with severe hypoxemia（1.28%）.70 patients with normal lung function（17.90%）,133 patients with mild injury（34.02%）,144 patients with moderate injury（36.83%）,44 patients with severe injury（11.25%）,and abnormal lung function rate of 82.10%.14 cases（3.58%）of disability level one,25 cases（6.40%）of level two,23 cases（5.88%）of level three,151 cases（38.62%）of level four,and 117 cases of level six（29.92%）,61 cases of level 7（15.60%）.2 PaO₂,FVC,and FEV₁ of patients with pneumoconiosis at different stages were statistically different（P<0.05）.There was no significant difference in FEV₁/FVC（P>0.05）.The abnormal oxygen partial pressure and lung function of patients with pneumoconiosis at different stages were different.The abnormal rates were statistically different（P<0.05）.The abnormal rates of patients with stage Ⅱ and Ⅲ pneumoconiosis were significantly higher than those of patients with stage Ⅰ.There were statistical differences in the levels of PaO₂ and FVC in patients with pneumoconiosis at different ages（P<0.05）.There were no significant difference in FEV₁ and FEV₁/FVC levels（P>0.05）.There was a statistical difference in abnormal oxygen partial pressure rates among different age groups（P<0.05）,and there was no statistical difference in abnormal pulmonary function rates（P>0.05）.There were statistically significant differences in PaO₂,FVC,FEV₁,FEV₁/FVC,abnormal oxygen partial pressure,and pulmonary function abnormality rates in patients with disability pneumoconiosis（P<0.05）.The pneumoconiosis stage,patient age,and disability level were all low.There was a positive correlation between the level of hypoxemia,and the level of pulmonary function impairment（P<0.05）.The higher the pneumoconiosis stage,the older the age,and the more severe the disability level,the more severe hypoxemia and pulmonary function damage were.3 There was a positive correlation between PaO₂ and FVC and FEV₁（P<0.05）,and no correlation with FEV₁/FVC（P>0.05）.The abnormal rate of pulmonary function was significantly higher than the abnormal rate of partial pressure of oxygen（82.10% vs 65.47%,P<0.05）.There was a positive correlation between the level of hypoxemia and the level of lung injury.The more severe the hypoxemia,the more severe the lung injury（=0.69,P<0.05）.The hypoxemia grade and lung function damage grade have poor consistency（Kappa=0.16,P<0.05）.The results of identification of disability grades of lung function were more severe than those of disability grades of blood gas analysis（P<0.05）,and their consistency was poor（Kappa=0.23,P<0.05）.4 The new grading interval of oxygen partial pressure was: PaO₂≥84mmHg was normal,80mmHg≤PaO₂<84mmHg is mild damage,60mmHg≤PaO₂<80mmHg was moderate damage,PaO₂<60mmHg was severe damage.5 The oxygen partial pressure was classified according to the new oxygen partial pressure grading interval,there was no statistical difference between the abnormal oxygen partial pressure rate and the abnormal pulmonary function rate（80.05% vs 82.10%,P>0.05）.They have moderate consistency（Kappa=0.60,P<0.001）.The results of the new oxygen partial pressure grading interval disability grade identification results and the pulmonary function disability grading identification results had strong consistency（Kappa=0.65,P<0.001）.The agreement rate between the new oxygen partial pressure grading interval and the lung function disability grade identification result was significantly higher than the existing oxygen partial pressure standard,as clearly demonstrated by the lung function disability grade identification result agreement rate（73.91% vs 41.69%,P<0.05）.Conclusions 1 The pneumoconiosis stage and age affected the partial pressure of oxygen and lung function within patients with pneumoconiosis.2 The two Blood gas analysis standards and lung function standards were quite different in terms of disability level identification,and the standard of blood gas analysis was low.3 The new classification interval of partial pressure of oxygen was in good agreement with the pulmonary function standard.Figure 6;Table 25;Reference 113...