Analysis Of Risk Factors For Urinary Tract Infection Of Escherichia Coli Produced By Community-derived Extended-spectrum β-lactamase

Objective: To analyze the detection and related risk factors of extended-spectrumβ-lactamase(ESBLs)Escherichia coli in urine culture of patients with urinary tract infections from community sources.Methods: The clinical data of community-sourced urinary tract infections whose midstream urine culture was discovered with Escherichia coli admitted to the First Affiliated Hospital of China Medical University from January,2017 to December,2018 were collected.The 132 patients were divided into ESBLs group and non-ESBLs group according to the results of urine culture,Logistic regression analysis of risk factors for urinary tract infection with Escherichia coli in ESBLs from community-derived and non-ESBLs groups.Results: 1.The univariate analysis showed that the ESBLs group and the non-ESBLs group had gender(P = 0.005),urinary tract obstruction(P = 0.019),previous hospitalization in the past 3 months(P = 0.027),and antibiotic treatment in the past 3months(P = 0.029)and indwelling double J tube(P = 0.037)were statistically significant(P <0.05).2.Acoording to the logistic regression analysis,the following were identified as independent risk factors: male gender(OR=4.702,95% CI=1.890-11.698,P=0.001),urinary tract obstruction(OR=0.264,95% CI=0.113-0.614,P=0.002)and previous hospitalization in the past 3 months(OR=2.960,95% CI=1.890-11.698,P=0.001).Conclusion: Male gender,patients with urinary tract obstruction,and previous hospitalization in the past 3 months are more likely to develop ESBLs Escherichia coli urinary tract infections.We shuould pay more attention to patients with the risk factors which we mentioned above,and take effective measures,reasonable choose anti-infective drugs to prevent further spread and proliferation.