Vitamin A、D Levels And Mycoplasma Pneumoniae In Children Correlation And Adjuvant Treatment Of Pneumonia

Objective:To compare the differences between vitamin A and vitamin D levels in children with mycoplasma pneumoniae pneumonia(Mycoplasma pneumoniae pneumonia,MPP)and healthy physical examination children;And to analyze the correlation between age,sex,vitamin A level and vitamin D level and the incidence of MPP in children;To evaluate the clinical efficacy of adjuvant vitamin A and vitamin D(vitamin AD drops)treatment;And to synthesize the above study,hoping to provide clinical basis for prevention and treatment.Methods:Over the period from December 2018 to December 2019,100 MPP children in pediatric inpatient treatment from the affiliated hospital of Yan’an University were randomly selected as the case group,and 50 healthy children with general conditions matching routine physical examination in our pediatric outpatient department were randomly selected as the healthy group,both of which tested and compared vitamin A and vitamin D levels;And the case-healthy age,sex,vitamin A deficiency and vitamin D inappropriate data were analyzed by two-classification Logistics regression analysis.The selected MPP children were numbered according to the order of admission time,the single number 50 cases entered the observation group,the double number 50 cases entered the control group,the control group MPP children were treated with azithromycin and symptomatic support treatment,the observation group MPP children were treated with vitamin AD drops on the basis of the treatment of the control group,and the clinical efficacy of the two groups was compared.Results:1.General data of children in case group and healthy group,such as sex and age,were not statistically significant(P>0.05),and the two groups were comparable.2.The vitamin A and Vitamin D levels of the children in the case group were significantly lower than those in the healthy group(P < 0.05).3.The vitamin A deficiency rate(including all types of deficiency)in the case group was statistically significant compared with that in the healthy group(P<0.05),and the deficiency rate was higher than that in the healthy group;The unsuitability rate of vitamin D in the case group(including severe deficiency,deficiency and lack)was statistically significant compared with the healthy group(P<0.05).4.Age,sex,vitamin A deficiency(including all types of deficiency)and vitamin D inappropriateness(including severe deficiency,deficiency,and lack)were analyzed with Logistics regression analysis of MPP onset,vitamin A deficiency and vitamin D inappropriateness were statistically significant(P < 0.05),the regression coefficients b1.066 and 1.804,and the OR values were 2.905 and 6.075,respectively.5.General data of children in the observation group and the control group,such as age and sex,were not statistically significant(P>0.05),and the two groups were comparable.6.Compared with the control group,the clinical efficacy index of the observation group and the control group,body temperature dropped to normal time,cough relief time and hospitalization time,the difference was statistically significant(P<0.05),and the observation group was shorter than the control group.Conclusion:1.Vitamin A deficiency(including all types of deficiency)and vitamin D inappropriateness in children(including severe deficiency,deficiency and lack)are associated with the onset of mycoplasma pneumoniae pneumonia.2.Children with mycoplasma pneumoniae pneumonia supplemented with vitamin AD drops can improve the therapeutic effect.