| Objective:To verify the clinical effect of Wushen Yangxin decoction in the treatment of chronic heart failure(Qi deficiency and blood stasis type),and to provide new ideas for the treatment of chronic heart failure by traditional Chinese medicine.Methods: The study cases were all from July 2018 to December 2019 in Heilongjiang University of traditional Chinese Medicine affiliated to the first Hospital of Cardiovascular Disease Department outpatient and ward diagnosis of chronic heart failure TCM syndrome differentiation Qi deficiency and blood stasis syndrome a total of 62 patients.The patients were randomly divided into the treatment group of 31 cases,the control group of 31 cases,the control group received basic western medicine treatment,the treatment group was given basic western medicine treatment at the same time plus or minus five ginseng Yangxin decoction treatment,the course of treatment was4 weeks.The cardiac function,B natriuretic peptide(NT-pro BNP)at the end of N,left ventricular ejection fraction(LVEF),walking distance of 6 minutes,changes in quality of life [modified minnesota heart failure quality of life scale(C-MLHFQ)],chinese medicine syndrome score,to study the effect of wushenyangxin decoction on patients with chronic heart failure(qi deficiency and blood stasis type).Result:1.Cardiac function status :86.66% in the treatment group and 73.33%in the control group,the effect of the treatment group was higher than that of the control group,and the difference was statistically significant(P<0.05).2.NT-pro BNP : There was no significant difference in plasma before treatment between the two groups(P>0.05).After 4 weeks of treatment,the curative effect of the treatment group was better than that of the control group,and the difference was statistically significant(P<0.05).3.left ventricular ejection fraction(LVEF): there was no significant difference between the two groups before treatment(P>0.05).After 4 weeks of treatment,the effect of the treatment group was better than that of thecontrol group,and the difference was statistically significant(P<0.05).4.walking distance of 6 minutes: there was no significant difference between the two groups before treatment(P>0.05).After 4 weeks of treatment,the curative effect of the treatment group was better than that of the control group,and the difference was statistically significant(P<0.05).5.quality of life [modified minnesota heart failure quality of life scale(C-MLHFQ)]: there was no significant difference between the two groups before treatment(P>0.05).After 4 weeks of treatment,the results of the treatment group were better than those of the control group,and the difference was statistically significant(P<0.05).6.TCM syndrome score: there was no significant difference between the two groups before treatment(P>0.05).After 4 weeks of treatment,the results of the treatment group were better than those of the control group,and the difference was statistically significant(P<0.05).he total effective rate in the treatment group was 90%,and the total effective rate in the control group was 76.66%,the difference was statistically significant(P<0.05).Conclusion:1.Wu Shen Yangxin decoction can effectively improve the heart function status and TCM syndromes of patients with qi deficiency and blood stasis syndrome of chronic heart failure.2.Wushen Yangxin decoction can reduce plasma NT-pro BNP level and increase ejection fraction in patients with chronic heart failure with qi deficiency and blood stasis.3.Wushen Yangxin decoction can increase the 6-minute walking distance and improve the quality of life of patients with chronic heart failure with qi deficiency and blood stasis. |
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