| ObjectiveTo explore the effectiveness of capsaicin atomization induced-cough on clearing respiratory secretions in stroke patients early after tracheotomy,in order to provide a new simple and effective sputum-promoting method for clinical patients,and provide reference and basis for clinical practice.MethodsThis study was a clinical randomized controlled trial.Stroke patients early after tracheotomy who were hospitalized in the First Affiliated Hospital of Soochow University from January 2019 to December 2019 were selected as the research subjects,and those who met the inclusion criteria were randomly divided into intervention group and control group.A total of 68 subjects were included in the study,including 34 in the intervention group and 34 in the control group.The control group was given routine nursing care after tracheotomy,while the intervention group was given 62.5 μmol/L capsaicin solution atomized on the basis of routine nursing care,4 times a day,and the duration of a single atomization was not more than 1 min(if the patient had 5 times coughs within 1 min of atomization,the atomization could be stopped;if the patient had<5 times coughs within 1 min,the atomization was continued for 1 min)for 1 week.The amount of daily sputum output and the number of daily suctions of the two groups patients before and during the intervention were observed.At the same time,compare the differences in sputum viscosity,cough function,clinical pulmonary infection score(CPIS),Substance P(SP),Glasgow score(GCS),and length of stay between patients in two groups before and after the intervention.In addition,the patient’s vital signs during capsaicin atomization and sputum suction were compared.All the data were analyzed statistically using SPSS 25.0 software.The difference was statistically significant with P<0.05.ResultsThere was no statistical difference in the basic data of the two groups of patients before the intervention(P>0.05).(1)Effect of sputum excretion:① Amount of daily sputum output:Before the intervention,there was no significant difference between the two groups of patients(P>0.05).During the intervention,the patients in the intervention group had more sputum excretion per day than the control group,and the difference was statistically significant(P<0.05).② Number of daily sputum suctions:Before the intervention,there was no significant difference between the two groups of patients(P>0.05).During the intervention,the number of daily sputum suctions in the intervention group was less than that in the control group.Although there was no significant difference between the two groups of patients on the 1st and 2nd day of atomization intervention,the difference was significant on the 3rd to 7th days(P<0.05).③ Viscosity of sputum:Before and after the intervention,there was no statistical difference in sputum viscosity between the two groups of patients(P>0.05).(2)Cough ability:There was no statistical difference in the cough reflex ability between the two groups of patients before the intervention(P>0.05).After one week intervention,there was no difference in the number of patients who could be induced to produce cough reflexes in the two groups(P>0.05),but the degree of cough reflexe in the intervention group was stronger than that in the control group(P<0.05).(3)CPIS:Before intervention,the CPIS scores of the two groups of patients were not statistically different(P>0.05).After one week intervention,the CPIS score of the patients in the intervention group were significantly lower than that in the control group(P<0.05).(4)SP:There was no significant difference in the serum SP level between the two groups of patients before the intervention(P>0.05).After one week of intervention,the SP level in patients of the intervention group was significantly higher than that in the control group(P<0.05).(5)Vital signs:Compared with sputum suction,there was no statistically significant differences in heart rate,respiratory rate,and blood oxygen saturation during capsaicin atomization.(P>0.05).(6)Others:There was no statistical difference in consciousness between the two groups of patients before and after the intervention(P>0.05).In addition,there was no significant difference in the length of hospitalization between the two groups of patients(P>0.05).Conclusions(1)Capsaicin atomization-induced cough could effectively promote sputum excretion and reduce the number of passive suction in stroke patients with tracheotomy,and has better safety.(2)Capsaicin atomization could increase the serum SP level,improve the cough function,and alleviate the development of lung infections of patients.(3)Capsaicin atomization had no significant effect on the sputum viscosity,consciousness,and length of hospital stay of patients,and needs to be further studied. |
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