| Objective:To investigate the distribution characteristics of TCM constitutions and syndrome types in some patients with rheumatoid arthritis in kunming,to explore the relationship between syndrome types,laboratory indexes and TCM constitution,in order to guide the formation of a personalized TCM prevention and treatment plan that takes into account the constitution bias.Method:A questionnaire survey was conducted on 300 RA patients who met the inclusion criteria.The basic information questionnaire and TCM constitution identification scale were filled out,and the constitution determination was made in combination with the table of TCM constitution classification and determination.Result:1 The general information(1)In this study,248 females and 52 males were involved,with the ratio of male to female being about 1:4.77.(2)The distribution of age was16 to 82 years old,the average age was 56 years old,40 to 59 years old was the peak incidence.(3)There were 129 cases(43.0%)who were farmers,and they were the population with high incidence of RA.(4)The shortest course was 1 month,the longest course was 50 years,and the most patients were distributed in 1 to 5 years.(5)The majority of RA patients had normal body mass index,and the underweight,overweight and obese patients were few.2 Differences of TCM constitution types in basic information,joint involvement and laboratory indexes(1)The proportion of mild quality was the largest(38.3%).Among the biased constitutions,yang-deficiency constitutions accounted for the majority(58.9%),and phlegm-dampness constitutions accounted for the least(2.2%),and there was no special constitution.(2)There were differences in the distribution of TCM constitution types among RA patients of different genders(P<0.05),among which the qi depression constitution were all female patients and the phlegm-dampness constitution were all male patients.(3)There was no statistical difference in the distribution of constitution types in RA patients of different ages(P>0.05).(4)There were differences in the distribution of constitution types among different disease courses(P<0.05),the shortest course of disease was the mild constitution,and the longest course was the blood stasis constitution.(5)There was a significant difference between body mass index range and distribution of constitution type(P<0.01),and the proportion of patients with normal BMI with yang-deficiency constitution was relatively large.(6)There was no statistical difference in the distribution of joint involvement,inflammatory index and immune index among different constitution types(P>0.05).3 Differences of TCM syndrome types in basic information,joint involvement and laboratory indexes(1)The proportion of wind-cold-dampness syndrome was the largest(57.7%),and the proportion of qi and blood deficiency syndrome was the least(2.3%).(2)There was no statistical difference in the distribution of TCM syndromes between genders(P>0.05),among which qi and blood deficiency syndrome were all female patients.(3)The distribution of TCM syndromes varied with different courses(P<0.05).Patients with wind-cold-dampness syndrome had the shortest course of disease,and those with phlegm and blood stasis syndrome had the longest course of disease.(4)There were differences in the distribution of TCM syndrome types in different age groups(P<0.05).The majority of patients aged 20-79 years were suffering from wind-cold-dampness syndrome.(5)There were significant differences in the distribution of TCM syndromes among different body mass indexes(P<0.01).Wind-cold-dampness syndrome was more common in patients with normal body mass index.(6)The differences in RF-Ig M distribution among different TCM syndromes were statistically significant(P<0.05),and RF-Ig M positive patients were mainly in wind-cold-dampness syndrome.(7)There was no significant difference in the distribution of TCM syndrome types and joint involvement,inflammatory index,RF-Ig A,RF-Ig G,anti-CCP and anti-AKA(P>0.05).4.There were significant differences in the distribution of TCM syndromes among different constitution types(P<0.01).Patients with qi-blood deficiency syndrome all had qi-deficiency constitution,those with blood-stasis constitution all had phlegm-stasis syndrome,and those with yin-deficiency syndrome all had deficiency syndrome of liver and kidney,wind-dampness-heat syndrome accounted for the highest proportion in patients with dampness-heat constitution(92.9%),wind-cold-dampness syndrome accounted for the largest proportion(76.1%)of patients with yang-deficiency syndrome.Conclusion:1 The susceptible constitution of some RA patients in kunming is yang-deficiency constitution,and the most common TCM syndrome type of RA patients in kunming is wind-cold-dampness syndrome.2 Gender,disease course and body mass index were correlated with TCM constitution type.Age,course of disease,body mass index and RF-Ig M were correlated with TCM syndromes.3 There was no correlation between age,joint involvement,laboratory index and physical type.There was no correlation between TCM syndrome types and gender,joint involvement,RF-Ig A,RF-Ig G,anti-CCP and anti-AKA.4 There were significant differences between the TCM syndrome type and the constitution type of RA patients,and the bias of the constitution may affect the TCM syndrome differentiation,so it is speculated that there is a correlation between them. |
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