Effects Of Percutaneous Coronary Interventions On Depression And/Or Anxiety In Patients With Acute Coronary Syndrome And Its Prognosis

Objectives: To investigate the prevalence of depression and anxiety on patients with percutaneous coronary interventions after acute coronary syndrome,the related factors of them,and their impact on clinical prognosis.Methods: According to the inclusion and exclusion criteria,248 patients were selected and divided into PCI group(138 patients)and non-PCI group(110patients).The depression and anxiety status of the patients in both groups were assessed by Generalized Anxiety Disorder Scale(GAD-7)and Patient Health Questionnaire Depression Scale-9(PHQ-9)one day before,within one week and 3 months after cardiac intervention.A 6-month clinical follow-up of patients with ACS after PCI was performed to record the occurrence of major adverse cardiovascular events(MACE).Results: One day before intervention:there was no significant difference in the prevalence of depression(34.8%,34.5%)and anxiety(29.0%,33.6%)between the two groups of patients;Within 1 week after intervention: the prevalence of depression(48.0%)or anxiety(42.0%)in the PCI group was significantly higher than that of preoperative and non-PCI groups;3 months after intervention: the prevalence of depression(44.0%)and anxiety(40.0%)in PCI group was higher than that of non-PCI group,But compared with that within one week after intervention there was no statistical difference.And women,living alone,and low education level,the more number of coronary artery lesions are independent risk factors for anxiety in patients undergoing PCI after ACS;living alone,low education level,and the more number of implanted stents are independentrisk factors for depression in patients undergoing PCI after ACS.6 months follow-up after PCI: The incidence of MACE was significantly higher in patients with depression(13.6%)and anxiety(14.5%)after PCI than that in non-depression and non-anxiety patients.Conclusion: PCI can increase the incidence of anxiety and depression in patients with ACS.Depression and anxiety in patients undergoing PCI after ACS can increase the incidence of MACE for 6 months.