| Objective:Through the observation of the therapeutic effect of channels-acupoints dredge plus pain point knead dial Massage manipulation combined with core stability exercise on chronic nonspecific low back pain and the influence on the serum inflammatory factors IL-6,TNF-α and serumβ-EP,the clinical effect and mechanism of channels-acupoints dredge plus pain point knead dial Massage manipulation combined with core stability exercise for chronic nonspecific low back pain were discussed,which provided new ideas and theoretical basis for the clinical treatment of chronic nonspecific low back pain.Method:Sixty patients with with chronic nonspecific low back pain who meet the inclusion criteria were randomly divided into the experimental group(30cases)and the control group(30 cases)according to the ratio of 1:1 by using the random number table.The experimental group was treated by channels-acupoints dredge plus pain point knead dial massage manipulation combined with core stability training,and the control group was treated with core stability training.Two groups of patients were treated for two weeks,the experimental group was treated once a day,five times a week;once a day,five times a week.The changes of VAS score,RMDQ score and SF-36 score before and after treatment were compared between the two groups.The levels of IL-6,TNF-α and β-EP in serum were measured by ELISA method before and after treatment.Result:(1)Comparison of VAS before and after treatment,there was no significant difference in VAS score between the two groups(P>0.05);after treatment,the VAS score of the two groups was significantly improved(P<0.05),and the improvement of the experimental group was better than that of the control group(P < 0.05),and the total effective rate of the experimental group was better than that of the control group(P<0.05).(2)Comparison of Roland Morris Disability Questionnaire(RMDQ)before and after treatment:there was no significant difference between the two groups before treatment(P>0.05);after treatment,the RMDQ scores of the two groups were improved(P<0.05),and the improvement of the experimental group was better than that of the control group(P < 0.05);(3)Comparison of the simplified health measurement scale(SF-36)before and after treatment: the two groups before treatment(SF-36)There was no significant difference in the scores,which was comparable(P>0.05).After treatment,SF-36 scores of the two groups were improved(P < 0.05),and the improvement of the experimental group was better than that of the control group(P<0.05);(4)Comparison of the levels of serum inflammatory factor IL-6,TNF-α and serum β-EP before and after treatment:there was no significant difference in serum IL-6,TNF-α and serumβ-EP between the two groups before treatment(P>0.05).After treatment,the levels of IL-6 and TNF-α in serum of the two groups were decreased(P<0.05),and the improvement of the experimental group was better than that of the control group(P<0.05);the level of β-EP in serum was increased(P<0.05),and the improvement of the experimental group was better than that of the control group(P<0.05).Conclusion:The treatment of chronic nonspecific low back pain by channels-acupoints dredge plus pain point knead dial massage manipulation combined with core stability exercise has a significant effect.Considering from the overall point of view,the treatment of TCM viscera,spleen,stomach,liver and the flexible personalized treatment,can more effectively relieve the low back pain,recover the low back function,improve the quality of life of patients,it is safe and easy to be accepted by patients.The combination of Channels-acupoints Dredge and Point Knead Dial Massage Manipulation with core stability exercise can significantly reduce the levels of IL-6 and TNF-α,and increase the content of opioid peptide β-EP in patients with chronic nonspecific low back pain,which may be one of the mechanisms for the treatment of chronic nonspecific low back pain. |
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