| Objective:Investigate erectile function and depression and anxiety in patients with hyposexuality,calculate their incidence,analyze the correlation between symptoms,understand the clinical characteristics of male hyposexuality;analyze serum sex hormone levels in patients with hyposexuality,and understand serum sex hormone levels in hyposexuality features are the theoretical basis for clinical diagnosis and treatment.Methods:From October 2017 to October 2019,134 cases of male outpatient clinics in Zhengzhou University First Affiliated Hospital were collected with low sexual desire as the main complaint or low sexual desire accompanied by ED.These patients were screened by Professor Wang Rui and diagnosed according to the diagnostic criteria of low sexual desire at home and abroad.They were quantified using the male 13 out-patient self-assessment scale for men.They were included in 68 cases of low sexual desire and normal sexual desire.There were 66 cases.The research content includes:(1)the general situation of all the patients(age,course of disease,occupation,education,number of morning eruption,frequency of sexual life);(2)the use of electrochemical luminescence in our hospital to detect the serum T,FSH,LH,E2,PRL levels;(3)Application of the International Erectile Function Rating Scale(IIEF-5)to assess erectile function in all patients;(4)Application of the Self-Depression Evaluation Tool(PHQ-9)and Generalized Anxiety Disorder Scale(GAD-7)assess the psychological status of the visitor.The general conditions,the incidence of erectile dysfunction,anxiety and depression,and the correlation between each symptom were compared between the low sexual desire group and the normal sexual desire group,and the five clinical characteristics of serum sex hormones in the low sexual desire group were analyzed.Results:The general situation and the results of the analysis of each symptom are as follows:in general,it is found that male sexual desire has nothing to do with age and is related to the onset of disease.29 people in the hyposexuality group had ED,and the incidence of ED was 42.65%,and 20 people in the normal sexuality group had ED,and the incidence of ED was 30.30%.The incidence of ED was different between the two groups(P=0.012);IIEF-5 score of the low libido group and normal libido group:(19.4±3.4)VS(23.2±3.1),there is a difference between the two(P=0.02);the number of morning eruption/month of the low libido group and the normal libido group:(3.5±1.8)VS(8.4±1.3),there is a difference between the two(P<0.001);the number of sexual lives/month of the low libido group and the normal libido group:(4.1±1.9)VS(5.7±1.7).There was a difference between them(P=0.03).Thirty patients(44.12%)in the low libido group had depressive disorder,which was significantly higher than 17(25.76%)in the normal libido group(P=0.003);16 patients(23.53%)in the low libido group had anxiety disorders and had normal sexual desire.There were no significant differences in the 11 patients(16.67%)in the group(P=0.076).Patients with low sexual desire had anxiety and depression,and the incidence of depression was higher.Patients with low sexual desire with ED had higher PHQ-9 scores than those without.Patients with hyposexuality with ED(8.87±5.27 VS 5.36±4.45),patients with hyposexuality with ED had higher GAD-7 scores than patients with hyposexuality without ED(7.85±4.56 VS 6.03±4.53),and The prevalence of anxiety and depression was significantly different between the two(P<0.05).Correlation analysis showed that there was no correlation between sexual desire score and IIEF-5 score(r=0.486,P=0.065),sexual desire score had correlation with PHQ-9(r=0.561,P=0.032),sexual desire score and GAD-7 correlation(r=0.536,P=0.042).The results of sex hormone analysis are as follows:T was different between the two groups(11.46±1.62)VS(17.51±3.68),(P=0.003);T/E2 was different between the two groups(12.42±1.38)VS(17.27±3.94,(P=0.001);there was no difference in E2 between the two groups(94.45±10.37)VS(114.38±14.72),(P=0.587);there was no difference in FSH,LH,and PRL.The correlation analysis conclusions are as follows:libido score and T,T/E2 correlation is good(r=0.535 and r=0.603),the difference is statistically significant(P<0.001),and the correlation with T/E2 is better;in addition,there is also correlation between T and T/E2,E2 The difference is also statistically significant(P<0.001).The areas under the ROC curves of T,E2,T/E2 are:0.660,0.527,and 0.669.When the value of T/E2 is 12.42～15.73,the diagnosis of low libido is The sensitivity and specificity are relatively high.Conclusions:(1)People with low libido have a higher incidence of anxiety and depression,and a higher incidence of depression.(2)People with low libido have a higher incidence of ED,and have low libido,ED,and anxiety and depression psychological disorders correlation,mutual influence and mutual deterioration.(3)T,T/E2 are both important influencing factors of male sexual desire,E2 may also be one of the influencing factors of male sexual desire.(4)Male sexual desire and the ratio of androgen to estrogen(T/E2)has a better correlation.When the range of T/E2 is 12.42～15.73,it indicates that sexual desire may be normal.If it exceeds this range,low sexual desire may occur regardless of high or low. |
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