Analysis On Characteristics Of The Metabolic Syndrome In Schizophrenic Long-term Inpatients

Objective: In recent years,with the widespread use of the second-generation antipsychotic drugs,the treatment of schizophrenia has been greatly improved,and the extrapyramidal reaction caused by antipsychotic drugs has gradually decreased,but it also brings some new adverse reactions.For example,weight gain,abnormal glucose and lipid metabolism,and the like.The latter not only affects patient compliance,but also affects the patient’s social function,and even causes serious physical illness.More and more medical research shows that the proportion of patients with schizophrenia complicated with metabolic abnormalities is significantly higher than that of the general population,which not only affects the quality of life of patients,but also affects their long-term prognosis.The use of new,more suitable diagnostic criteria for metabolic syndrome in the Chinese population has rarely been reported on the incidence of metabolic syndrome in patients with long-term hospitalization of schizophrenia.This study used long-term hospitalization for schizophrenia patients.Subjects,using the latest diagnostic criteria for metabolic syndrome based on research evidence from the Chinese population,conducted general data questionnaires and laboratory tests to attempt to describe the prevalence and prevalence of metabolic syndrome in patients with long-term hospitalized schizophrenia.Methods: This study was a cross-sectional survey using a general data questionnaire for self-made inpatients with schizophrenia.The main statistical data of the patients included in the questionnaire were gender,age,etc.,as well as height,weight,and waist circumference measured after admission.Blood pressure,blood lipids,etc.,including medications used,time of administration,history of diabetes,history of hypertension,smoking,duration of mental illness,and medications for antipsychotics.The quality of life of patients with long-term hospitalized schizophrenia was investigated using the Quality of Life Assessment Comprehensive Questionnaire(GQOL I-74).Statistical analysis was performed using SPSS 18.0 software.Results: A total of 183 patients were enrolled in this study,including 95 males(52%)and 88 females(48%).Long-term hospitalization of patients with schizophrenia andmetabolic syndrome,older,smoking,anti-schizophrenia drugs for a longer time,the metabolic syndrome is more likely.Among the patients surveyed,atypical antipsychotics were the majority,and clozapine,risperidone,olanzapine,and quetiapine were used at 73.2%,and chlorpromazine in the first generation of antipsychotics.The use rate of phenazine and sulpiride reached 20.2%.The second-generation antipsychotic drugs were associated with a greater risk of metabolic syndrome.In the second generation of antipsychotic drugs,olanzapine has a higher risk of causing metabolic syndrome.The quality of life assessment questionnaire(GQOL I-74)was used to investigate the quality of life and social function of patients with long-term hospitalized schizophrenia.According to the comprehensive quality of life assessment questionnaire,schizophrenia was used in terms of physical function,mental function,social function and total score.The scores of patients with metabolic syndrome were lower than those of patients with non-combined metabolic syndrome.Conclusion: In this study,long-term hospitalization of schizophrenia patients,the combined occurrence of metabolic syndrome ratio,the occurrence of metabolic syndrome and age,long-term medication,smoking and atypical antipsychotic drugs,especially the Austrian nitrogen.There is a relatively close relationship.In the treatment of long-term hospitalized schizophrenia patients,smoking cessation treatment should be strengthened,and it is recommended for patients with older age,longer drug treatment,and patients with the second-generation antipsychotic drugs,especially olanzapine.Detect relevant metabolic indicators to reduce the risk of metabolic syndrome.