Different Types Of Eczema And Its Severity Correlation Between Peripheral Blood EOS And Serum IgE In Lanzhou

Objective:By detecting the EOS level,serum IgE level and severity of the disease in patients with different types of eczema,the correlation between eczema and severity of different syndrome types and EOS levels and serum IgE levels in peripheral blood 2was explored.To provide more targeted life guidance for patients with different syndrome differentiation and type of eczema in Lanzhou area,to prevent the occurrence of the disease,and to provide a theoretical basis and data support for the evaluation of peripheral blood IgE and EOS in different types of eczema detection.Methods:Collecting the dermatology of 5 hospitals including the 940th Hospital of the People’s Liberation Army Joint Service and Anning Branch,the Gansu Provincial Cancer Hospital,the Gansu Provincial Hospital of Traditional Chinese Medicine,and the Affiliated Hospital of Gansu University of Traditional Chinese Medicine.December 2017-2018 420 cases of eczema patients who were diagnosed by immunological imprinting(lgE,sIgE)and assessed in terms of severity of illness in the outpatient and inpatient departments during December(IgE and EOS in peripheral blood of patients with different types of eczema)Example),(180 cases of the relationship between the severity of different types of eczema and peripheral blood IgE,EOS),and then according to the TCM classification criteria,the two groups of patients were divided into wet heat immersion syndrome group,spleen deficiency and wetness syndrome group,blood deficiency The wind-drying syndrome group was determined by the Chinese medicine department of the 940th Hospital of the Joint Service of the People’s Liberation Army and the review of the above physicians;the data were analyzed and analyzed by SPSS22.0 software.The statistical results were statistically significant at P<0.05.Results:The first part The relationship between different types of eczema patients with serum IgE,EOS1.Among the 240 patients with eczema,182(75.83%)were positive for total serum IgE.Among them,the positive rate of total IgE in serum of damp heat immersion syndrome group,spleen deficiency dampness syndrome group and Xuexufeng dryness syndrome group were 72.50%,85.25%and 68.75%,respectively.The chi-square test was performed between the three groups of data(c~2=7.412,p<0.05).The difference of serum total IgE between the damp-heat syndrome group and the spleen-deficiency syndrome group was statistically significant(c~2=4.619,p<0.05),there was no significant difference in serum total IgE between the damp-heat syndrome group and the Xuexufeng dryness syndrome group(c~2=0.271,p>0.05),serum total IgE in the spleen-deficiency and dampness syndrome group and Xuexufeng dryness syndrome group.The difference in test results was statistically significant(c~2=7.025,p<0.05).2.The positive rate of inhaled allergens in 240 patients with eczema was higher than that in allergens.182 patients were positive for inhaled allergens(positive rate 75.83%),and 158 patients were positive for allergens(positive rate 65.83%);The two sets of data were tested by chi-square test.There was a statistically significant difference between inhaled allergens and allergens in patients with eczema(c~2=5.808,p<0.05).3.The serum sIgE levels of eczema patients in Lanzhou area increased in different degrees.The positive rates of inhaled allergens in the damp-heat syndrome group,spleen-deficiency syndrome group and blood-deficiency syndrome group were:90.00%,67.50%,70.00%;The data of the group were analyzed by chi-square test.The difference between the three types of inhaled allergens was statistically significant(c~2=13.278,p<0.01).There were significant differences in the inhaled allergens between the damp-heat syndrome group and the spleen-deficiency syndrome group(c~2=12.101,p<0.01).The inhaled allergens in the damp-heat syndrome group and the blood-deficiency syndrome group were significantly different.Statistical significance(c~2=15.504,p<0.01);there was no significant difference in inhaled allergens between the spleen-deficiency and dampness syndrome group and the Xuexufeng dryness syndrome group(c~2=0.110,p>0.05).The positive rates of allergens in the hot and humid immersion syndrome group,the spleen deficiency and dampness syndrome group,and the blood deficiency and dryness syndrome group were:60.00%,58.89%,and 63.75%,respectively.The chi-square test was used for the three groups of data(c~2=0.259,p>0.05)There was no significant difference between the three syndrome types of allergens.4.Among the syndromes of traditional Chinese medicine for eczema patients in Lanzhou are a,the positive rate of allergens in the inhaled allergens,dwarf ragweed,arborvitae,punctate/branches/smoke/black koji/stigma The positive rate of sputum,cashew and mango in the all ergens was higher;the spleen deficiency and dampness syndrome group inhaled the allergen s of house dust mites,dwarf ragweed,wormwood grass carp,cypress cypress,cypress,birc h,walnut,paulownia yang and dwarf ragweed The positive rate of Artemisia scoparia L.w as higher,and the positive rate of sputum,mango and milk in the allergens was higher.Th e blood deficiency syndrome group inhaled the allergens,such as house dust mites,cypress sap,saplings,saplings,pecans,and dog fur.The positive rate of dandruff was higher;the positive rate of mango,medlar and cashew was higher in allergens.5.There were 38 patients(15.83%)with elevated EOS in peripheral blood of 240 patients with eczema.Among them,the elevated rates of EOS in the peripheral blood of the damp-heat immersion syndrome group,the spleen-deficiency syndrome group,and the blood-deficiency syndrome group were 26.25%,12.50%,and 8.75%,respectively.Chi-square test was performed between the three groups of data(c~2=10.193,p<0.05).The difference of EOS between the damp-heat syndrome group and the spleen-deficiency syndrome group was statistically significant(c~2=4.841,p<0.05),the difference of EOS test results between the dampness and heat syndrome group and the blood deficiency and dryness syndrome group was statistically significant(c~2=8.485,p<0.05),the spleen deficiency and dampness syndrome group and the blood deficiency and dryness syndrome group peripheral blood EOS There was no significant difference in the test resultsc~2=0.592,p>0.05).The second part The relationship between the severity of different types of wet sore disease and serum IgE,EOSA total of 139 patients(77.22%)with elevated tIgE in 180 patients with wet sore,including 60patients with tIgE and 60 patients with spleen deficiency syndrome group,spleen deficiency and dampness syndrome group and Xuexufeng dryness syndrome group The proportions were 44(73.33%),52(86.67%),and 43(71.67%).There was no correlation between the severity of eczema and tIgE in the damp-heat syndrome group(r=0.017,p>0.05).There was no correlation between the severity of eczema and tIgE in the spleen-deficiency syndrome group(r=-0.063,p>0.05).There was no correlation between the severity of eczema and tIgE in patients with blood deficiency and dryness syndrome(r=-0.063,p>0.05).2.A total of 27 patients(15.00%)with elevated EOS in 180 patients with eczema,including 60patients with hot and humid immersion syndrome group,spleen deficiency and dampness syndrome group,and Xuexufeng dryness syndrome group,the number and proportion of patients with elevated EOS There were 11 cases(18.33%),8 cases(13.33%),and 8 cases(13.33%).The severity of eczema in the damp-heat syndrome group was positively correlated with EOS(r=0.570,p<0.05).The severity of eczema in the spleen-deficiency syndrome group was positively correlated with EOS(r=0.316,p<0.05);blood deficiency The severity of eczema in patients with wind-dry syndrome group was positively correlated with EOS(r=0.338,p<0.05).Conclusion:The first part The relationship between different types of eczema patients with serum IgE,EOS1 The positive rate of total IgE in the spleen deficiency and dampness syndrome group of the patients with wet sore in Lanzhou area was significantly higher than that of the damp heat immersion syndrome group and Xuexufeng dryness syndrome group.It is suggested that spleen deficiency and dampness are the main potential pathogenesis of patients with wet sores in Lanzhou.2 Ingestion of allergens and inhaled allergens are associated with the onset of wet sore in Lanzhou,where allergens are higher than allergens.It is suggested that when the body is in a high-sensitivity state,environmental factors and dietary factors are related to the occurrence of wet sore,and environmental factors may participate more in the pathogenesis than in the diet.3 The incidence of wet sore disease in Lanzhou area is related to the change of EOS level in peripheral blood,especially in the hot and humid immersion syndrome group,suggesting that EOS may be involved in the occurrence of wet sore syndrome.4 Wet sore disease is an allergic disease caused by a variety of internal and external factors.Therefore,allergens are screened for patients with wet sores,peripheral blood EOS is checked,and desensitization treatment is timely according to the results of inhaled allergen test.Choosing a suitable living environment,formulating a diet plan that suits one’s own quality,and rotating or ingesting the allergens may reduce the frequency of disease occurrence and recurrence,and further improve the quality of life of patients.The second part The relationship between the severity of different types of wet sore disease and serum tIgE,EOS1 There was no correlation between the severity of different types of wet sores in Lanzhou and the positive rate of tIgE.2 The severity of different types of wet sore disease in Lanzhou area was positively correlated with the positive rate of EOS.