The Performance Evaluation Of Breast Cancer Diagnosis With Mammography And Magnetic Resonance Imaging

Objects:To explore and compare the clinical values of mammography and magnetic resonance imaging(MRI)in the diagnostic accuracy of breast cancer.Methods:96 suspected breast cancer patients(26 to 75 years old)from July 2011 to June2017 in our hospital were selected.All patients underwent mammography,MRI within one month.Two experienced imaging physicians analyzed the diagnosis results in the absence of pathological findings.The pathological results were gold standard.The positive predict value(PPV),negative predict value(NPV),sensitivity,specificity of double imaging modalities were analyzed and compared by constructing a summary of receiver-operating characteristic(ROC)curves,area under the ROC curve(AUC)and ROC space.Results:The coincidence rate of MRI in the diagnosis of benign and malignant breast lesions was 74.0%,the rate of missed diagnosis was 6.7%(3/45),the rate of misdiagnosis was 43.1%(22/51),and the coincidence rate of mammography for the diagnosis of benign and malignant breast lesions was 70.8%.The rate of missed diagnosis was 17.8%(8/45)and the rate of misdiagnosis was 39.2%(20/51).Two techniques had a PPV lower than 65.6% in identifying the presence of malignant tumors.The NPV of MRI(90.6%)was higher than mammography(79.5%).The sensitivity and AUC of MRI were significantly higher than mammography(P<0.0001).Conclusions:The accuracy,sensitivity,and AUC of MRI in the diagnosis of breast lesions are higher than mammography.the performance of MRI is better than mammography in distinguishing malignant from benign breast carcinoma.