Correlation Between TCM Syndromes And Pathological Features And Ki-67 After Breast Cancer Surgery

Objectives By analyzing the clinical distribution characteristics of TCM syndromes after breast cancer surgery and its correlation with surgical methods,age and pathological parameters,it is expected to provide an objective basis for postoperative dialectics of breast cancer.Methods Included in the 178 patients who met our subject from February 2017 to February 2019 and met the subject conditions.On the 5th day after surgery,pathological information,TCM syndrome types and general data were collected.After statistical analysis,the correlation between postoperative breast cancer type and surgical procedure,age,pathological features,and Ki-67 was explored.Results 1.178 female patients,spleen and stomach disharmony accounted for 53.93%,liver and kidney yin deficiency syndrome accounted for 29.78%,qi and blood deficiency syndrome accounted for 16.29%.2.Statistical analysis,total mastectomy plus sentinel lymph node biopsy,total mastectomy plus sentinel lymph node biopsy plus axillary lymph node dissection,modified radical treatment of the syndrome distribution,the difference was not statistically significant(P> 0.05).There were statistically significant differences in the distribution of syndromes aged ≤35 years,35-65 years,and >65 years(P<0.05).Patients in the group of ≤35 years old were spleen and stomach disharmony syndrome;35-65 years old patients were more common with spleen and stomach disharmony(56.10%).3.The distribution of TCM syndromes in lymph node,clinical stage and molecular typing was statistically significant(P<0.05).Among them,lymph node positive was more common in non-spleen and stomach syndrome(57.89%);lymph node negative group was more common in spleen and stomach syndrome(62.75%).In the clinical stage I,the spleen and stomach disharmony syndrome and liver and kidney yin deficiency syndrome were common,accounting for 55.17% and 31.04% respectively;the clinical phase II was the most spleen and stomach disharmony(59.38%),and the liver and kidney yin deficiency syndrome was the second(28.12%).The type of tube type A was the most in the spleen and stomach syndrome(66.67%),followed by the liver and kidney yin deficiency syndrome(29.41%);the tube type B syndrome type was more than the spleen and stomach syndrome(53.73%);Her-2 overexpression type is rare with qi and blood deficiency syndrome(13.16%).There was no significant difference in the distribution of TCM syndromes between tumor diameter,vascular tumor thrombus,histological grade,pathological type,ER expression and PR expression(P>0.05).4.Ki-67<14% group and ≥14% group syndrome type distribution,the difference was statistically significant(P<0.05),<14% group was the most spleen and stomach syndrome(64.38%),liver and kidney yin deficiency syndrome Second(27.40%).Conclusions 1.In the early and middle stages of breast cancer,the syndrome type is more common in the spleen and stomach syndrome,the liver and kidney yin deficiency syndrome,and the qi andblood deficiency syndrome.2.Postoperative syndrome types of breast cancer were correlated with age,lymph node status,clinical stage,molecular type,and Ki-67.Postoperative syndromes could be inferred by age and these pathological parameters.The age is not more than 65 years old,the node is negative,the clinical stage is stage I or II,the molecular type is tube type A or tube type B or Her-2 overexpression type,and the patient type of Ki-67 <14% gives priority to spleen and stomach.And the card,followed by the liver and kidney yin deficiency syndrome,generally do not consider the qi and blood deficiency syndrome.3.Postoperative breast cancer syndrome and surgical methods,tumor diameter,vascular tumor thrombus,histological grade,pathological type,ER expression,PR expression were not correlated,surgical methods and these pathological parameters for breast cancer postoperative syndrome Type speculation has no reference value.