| Objective:To investigate the nutritional risk in patients with ulcerative colitis(UC),to analyze its related factors and the relationship with clinical outcomes,and survey the nutritional treatment in UC.Methods:We retrospectively investigated the clinical data of all the patients diagnosed as UC in Department of Gastroenterology,the Second Hospital of Hebei Medical University from January 2016 to December 2018.Using NRS2002 nutritional risk of the patients were evaluated.The demographic characteristics,clinical features,lab examinations,clinical outcomes and nutritional treatment of patients with nutritional risk were analyzed,comparing with those without nutritional risk during the same period of hospitalization.SPSS software was used for statistical analysis.Result:A total of 379 UC patients were enrolled in this study,including 204males and 175 females.222 UC patients were diagnosed with nutritional risk,the nutritional risk rate was 58.6%,and the lower was 53.03%,the higher was5.54%.153 UC patients who hospitalized in 2018 were enrolled in this study,including 66 patients who accepted nutritional treatment,the rate of nutritional treatment was 43.1%.1.Nutrition risk in male and female were 50.5%and 68.0%;the median age was 39(30.0,55.0)years old in the nutrition risk group,it’s 48(38.0,56.5)years old in the non-nutrition risk group;nutrition risk in patients aged≤44years,45-59 years and≥60 years were 68.1%,44.4%and 58.9%;the median BMI was 19.91(18.37,22.04)kg/m~2 in the nutrition risk group,it’s(22.18,26.20)kg/m~2 in the non-nutrition risk group;nutrition risk in patients with BMI less than 18.5 kg/m~2,18.5-24.0 kg/m~2 and more than 24.0 kg/m~2 were100.0%,65.1%and 22.4%;nutrition risk in mild,moderate and severe patients were 32.4%,45.7%and 85.0%;nutrition risk in E1,E2 and E3patients were 31.8%,38.3%and 66.7%.There were statistically significant differences(P<0.01).There was no significant difference in the duration and clinical classification.2.In the nutrition risk group,105/222(53.6%)patients complicated with infection,161/222(72.5%)patients complicated with anemia,138/222(62.6%)patients complicated with hypoalbuminemia,139/222(62.6%)complicated with electrolyte disturbance,and 31/222(16.3%)patients complicated with hypoglycemia.The hospitalization time was 21.5(13.0,28.0)days,and the median hospitalization cost was 23189(15989,33407)yuan.In the non-nutrition risk group,the cases were 54/157(34.4%),49/157(31.2%),31/157(19.7%),61/222(38.9%),2/157(1.3%),14.0(9.0,21.5)days,12951(9338,20241)yuan.There was statistically significant differences(P<0.01).There was no significant difference in electrolyte disturbance.3.In the nutrition risk group,56/80(70.0%)patients received nutritional treatment in hospital,including 3/56(5.4%)EN,39/56(69.6%)PN,14/56(25.0%)EN and PN;in the non-nutrition risk group,the cases were 10/73(13.7%),including 2/10(20.0%)EN,7/10(70.0%)PN,1/10(10.0%)EN and PN.There were statistically significant differences(P<0.01).Conclusion:1.The incidence of nutritional risk in UC was as high as 58.6%.2.Female was tend to be at higher nutritional risk.In addition,the lower BMI was,the more severe disease was,the more extensive lesions was,the incidence of nutritional risk was higher.3.The incidence of complications such as infection,anemia,hypoalbuminemia,electrolyte disturbance and hypoglycemia was significantly increased in patients with UC with nutritional risk,and the length of hospital stay and hospital costs were significantly prolonged.4.Both neglect and abuse exist in nutritional treatment in UC.Moreover,the application of EN is poor. |
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