Clinical Observation On Treatment Of Cold And Damp Stagnation Type Nodular Erythema

Objective:To observe the changes of TCM syndromes and related laboratory test indicators before and after treatment of patients with cold dampness and phlegm-type erythema by observing the treatment of Wutou Decoction,and to explore its clinical efficacy.Methods: Seventy-two patients with nodular erythema due to cold-dampness obstruction were selected.According to the simple randomization method of looking up random number table,odd numbers were classified into treatment group,even numbers were classified into control group,36 cases were divided into treatment group and 36 cases were divided into control group.Aconitum Decoction was added and subtracted for 6 weeks.The data of TCM syndromes(pain,purpura,erythema,nodules,local edema),treatment efficiency,laboratory test index,re-hospitalization rate in January and February after treatment were collected before and after treatment.The therapeutic effect was evaluated by comparing the improvement of each index before and after treatment.Result: 1.Compared with the control group,the total score of TCM syndromes in the treatment group was better than that in the control group,with statistical significance(P<0.05).2.Compared with the control group,the laboratory test indexes of the patients in the treatment group decreased significantly after treatment,with statistical significance(P<0.05).3.Compared with before treatment,the total effective rate after treatment is92%,indicating that the treatment is effective.4.The treatment group of Aconite Decoction for 6 weeks was also better than the control group in preventing the recurrence of erythema nodosa patients taking indomethacin for 6 weeks.Conclusion:1.Modified Wutou Decoction is superior to indomethacin in alleviating clinical symptoms of nodular erythema due to cold-dampness obstruction.2.Modified Wutou Decoction is superior to indomethacin in the treatment of nodular erythema due to cold-dampness obstruction.3.Modified Wutou Decoction is superior to indomethacin in reducing the recurrence rate of nodular erythema due to cold-dampness.