Comparative Observation Of Multispectral Imaging And Traditional Multi-mode Fundus Imaging On Choroidal Osteoma

Objective: To compare the fundus morphology and characteristics of multispectral imaging and traditional multi-mode fundus imaging in patients with choroidal osteoma.Methods: Four eyes of three patients diagnosed with choroidal osteoma by ocular ultrasonography and orbital CT were enrolled in this study.All patients underwent multispectral imaging(MSI)and traditional multi-mode fundus examination,including fundus color photography and enhanced-depth imaging-optical coherence tomography(EDI-OCT),autofluorescence(AF),fluorescein fundus angiography(FFA).Comparative analysis of choroidal osteoma taken by multispectral imaging and traditional multi-mode fundus imaging was performed,and the characteristic presentation of osteoma in MSI is analyzed,with the its conclusive diagnostic value is also comprehensively evaluated.Results: Choroidal osteoma has its own specific characteristic features in orbital CT and ocular ultrasonography,but it is not specific to judge whether the tumor is calcified and distinguish between calcified and non-calcified areas.The main significance of MSI for choroidal osteoma is to observe the decalcification of osteoma and to evaluate the development of the patient’s eye condition and predict the prognosis of the patient’s eye.It is also very sensitive to the accumulation and loss of the retinal pigment epithelial layer.In comparision,OCT is the most sensitive examination tool to detected subretinal fluid and exudative retinal detachment shown in choroidal osteoma,but there is possibility of missed-out lesions in the scanning interval,and OCT can not completely distinguish the boundary between calcification zone and decalcification zone,only regional observation.Fundus autofluorescence plays an important role in assessing the function of retinal pigment epithelial cells,but not sensitive to other aspects.The primary clinical value of FFA is the diagnosis of choroidal osteoma complicated with choroidal neovascularization and the assessment of its prognosis,which is otherwise insensitive.Conclusions:1.Multispectral imaging is superior to other traditional ophthalmic imaging examinations in the observation of calcification/decalcification of choroidal osteoma,and preliminary assessment of the course of disease and visual prognosis of patients with choroidal osteoma;2.multispectral imaging clearly shows the loss and accumulation of retinal pigment epithelium,which corresponds to OCT,FFA and fundus autofluorescence;3.Multispectral imaging for choroidal osteoma with subretinal effusion,exudative retinal detachment and choroid neovascularization is not sensitive and needs to be combined with OCT,FFA and other tests.In summary,multispectral imaging technology has a certain significance for the auxiliary diagnosis,observation and preliminary judgment of choroidal osteoma,and it can not completely replace other examinations.It needs to be combined with other traditional multi-mode fundus imaging to be more effective comprehensive understanding of the complications of choroidal osteoma more comprehensively.