| Obj ective:The purpose of this study was to investigate the clinical characteristics of women with acute myocardial infarction(AMI)at different ages,and to provide evidence for early prevention of high-risk womenMethods:370 patients with AMI admitted to the Department of Cardiovascular Medicine,First Hospital of Shanxi Medical University from June 1,2015 to January 31,2018,including 280 males and 90 females,were selected.The data of age,risk factors of cardiovascular diseases,Killip classification,laboratory examination,electrocardiogram manifestations and characteristics of coronary artery lesions were collected.The data were tested by SPSS19.0 software X 2and t test.Results:1.Among AMI patients under 50 years old,①the proportion of women with history of hypertension,diabetes mellitus and smoking was lower than that of men,and the proportion of women with family history was higher than that of men,there was significant difference between the two groups(P<0.05);(2)the average age of onset in women was slightly older than that in men[(45.83士6.478)岁 vs(42.97±6.288)岁,P>0.05],but there was no significant difference between the two groups;③the proportion of Killip grade I was higher than that of males,and the proportion of grade Ⅱ,Ⅲ and Ⅳ was lower than that of males,there was significant difference between the two groups(P<0.05);④the average level of troponin peak in females was lower than that in males[(13.26±36.103)ug/L vs(25.92±75.013)ug/L,P<0.05],but there was no significant difference in the average levels of blood lipid and N-terminal pro-brain natriuretic peptide in both groups;⑤Compared with males,the proportion of non-ST-segment elevation AMI in females was higher,and the proportion of coronary artery lesions manifested as single-vessel lesions was higher,and the proportion of multiple-vessel lesions was lower,there was significant difference between the two groups(P<0.05);⑥The proportion of females choosing selective percutaneous coronary intervention plus drug therapy and single-drug conservative treatment was higher than that of males,the proportion of emergency percutaneous coronary intervention plus drug therapy was lower than that of men,and there was significant difference between the two groups(P<0.05).2.Among AMI patients over 50 years old,①the average age of onset in women was significantly higher than that in men[(70.79±8.621)岁 vs(65.05±9.850)岁,P<0.01],there was significant difference between the two groups;②The proportion of hypertension,diabetes and family history in women was higher than that in men,but the proportion of smoking history was lower than that in men,and the difference between the two groups was statistically significant(P<0.05);The average levels of serum total cholesterol,serum low density lipoprotein cholesterol,serum low density lipoprotein cholesterosterol and N-terminal brain natriuretic peptide precursor peak were higher than men {[(4.85±1.119)mmol/L vs(4.13±1.012)mmol/L,P<0.01]、[(2.97±0.93 5)mmol/L vs(2.43 ± 0.795)mmol/L,P<0.05]、[(5896.63±7562.834)pg/ml vs(2841.25±6562.329)pg/ml,P<0.01]},however,the average level of troponin peak in the two groups was not significant;④The ECG manifestations and treatment options of female patients over 50 years old are the same as those of female patients under 50 years old,but the proportion of coronary artery lesions manifested as multi-vessel lesions or left main artery lesions is higher than that of male patients.The proportion of Killip grade I is lower than that of male patients,while the proportion of grade Ⅱ,Ⅲ and Ⅳ is higher than that of male patients,there was significant difference between the two groups(P<0.05)Conclusion:Compared with male patients with AMI,the average age of onset of female patients is older,the proportion of family history is higher,but the smoking rate is lower.Secondly,the proportion of female patients with non-ST-segment elevation AMI is higher The proportion of patients who choose selective percutaneous coronary intervention plus drug therapy and single drug conservative treatment is higher The proportion of patients who choose emergency percutaneous coronary intervention plus drug therapy is lower However,compared with male AMI patients of the same age group,female patients under 50 years old have a lower proportion of history of hypertension and diabetes mellitus,mild coronary artery disease and relatively good cardiac function,while female patients over 50 years old have a higher proportion of history of hypertension and diabetes mellitus,severe coronary artery disease and poor cardiac function.Therefore,women of different ages need to be given targeted and different interventions. |
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