The Study Of Moving Cupping Therapy On Curative Effects And Regeneration In Patients Of Chronic Lumbar And Back Pain

PurposeThrough moving cupping on the patients of chronic lumbar and back pain,to observe the degree of symptom improvement and the changes of inflammatory factors and stem cell chemokines in patients with chronic lumbar and back pain before and after treatment.The preliminary study of therapeutic effect and regeneration of moving cupping on chronic lumbar and back pain laid the foundation for further research on acupuncture and moxibustion in promoting tissue regeneration.Materials and MethodsSixty-three outpatients with chronic lumbar and back pain,who recruit from acupuncture and moxibustion department,were included in the study during September in 2018-April in 2019.The selection was in accordance with the diagnostic criteria,inclusion criteria and exclusion criteria.A round cup made of thick glass was used for moving cupping and retaining cupping on the back along the Bladder Meridian running course in bilateral sides,once every three days,the treatment for three times was as one course.Venous blood was drawn respectively from the elbow before the first treatment and on the third day(11 days)after the treatment.We observed the following:(1)Subjective index:the internationally recognized visual analogue scale for pain(VAS),Oswestry disability index(ODI),Japanese orthopedic association low back pain score(JOA)was used to evaluate the degree of pain before and after treatment;(2)Objective index:lumbar range of motion,the changes of serum levels of interleukin factors and tumor necrosis factors before and after the treatment by ELISA;the changes of stromal cell-derived factor-1 and CXC chemokine receptor 4 before and after the treatment by RT-PCR.The data of the study were analyzed by SPSS20.0,P<0.05 shows that the difference was statistically significant.Results(1)Subjective index:The VAS scores,ODI,JOA scores of these outpatients decreased after the treatment.The difference was statistically significant(P<0.05).(2)Objective index:The angle of lumbar was improvement.In the Interleukin and the tumor necrosis factors,IL-2 was increased than before treatment,and IL-6,IL-8,TNF-a decreased than before treatment significantly(P<0.001);In the chemokine factors,SDF-1 has increasing trend than before treatment and CXCR4 has decreasing trend than before treatment,that has statistically significant(P<0.05).Conclusion(1)Moving cupping can release the symptom of chronic lumbar and back pain effectively,while improve the quality of life;(2)Moving cupping therapy can reduce VAS pain score effectively;(3)Moving cupping therapy maybe regulate the environment of infflammation through decreased the level of pro-inflammation factors and increased the level of IL-2;(1)After moving cupping therapy,SDF-1 maybe promote the concentration gradient of migration between bone marrow and peripheral blood in vivo,it may promote tissue regeneration;...