Clinical Study Of Respiratory Baduanjin In Patients With Chronic Obstructive Pulmonary Disease

ObjectiveTo evaluate the clinical efficacy and safety of respiratory Baduanjin in patients with severe and extremely severe COPD in stable stage.Methods19 patients were randomized into control arm,14 were into lip-abdominal breathing group,and 19 were respiratory Baduanjin.Control arm were subjected to western and traditional Chineses medicine,lip-abdominal respiration was added in group 2,while respiratory Baduanjin was added in experiment.The study lasted for 12 weeks.CAT,mMRC,BMI index,6WMD,pulmonary function,respiratory muscle function and BODE index were compared between the three arms.Results52 patients were enrolled in the current study from May 2018 to January 2019 from Guangdong Provincial Hospital Dada Road General Hospital,50 cases were completed finally(1 removed and 1 missed),among which 18 were divided into the experiment group(1 removed),and 14 cases were in the lip-abdominal breathing group,18 were control group(1 missed).1.Baseline ConditionsParticipants were comparable in terms of demographic data,baseline status of height,weight,smoking history,drug use and treatment.2.CAT scoreCompared with the group,The CAT score was decreased in fourth week,eighth week and twelfth week in experiment arm(F=8.639,P=0.001<0.05).The inter-subjective effect between three groups were statistically significant(F=3.894,P=0.027<0.05),while had no significant difference between time and group(F=1.178,P=0.325>0.05).The CAT score of lip-abdominal breathing group was getting lower than first in fourth week and eighth week(P<0.05),while had no significant difference after twelfth week of treatment(P>0.05).There was no statistical significance in control arm(P>0.05).Between the groups,CAT score of the experiment arm was lower than the lip-abdominal breathing group in eighth week and twelfth week(P<0.05),while had no significant difference between the experiment and the control arm(P>0.05).3.mMRCIntra-group or inter-group comparisons,mMRC showed no significant difference between three groups(P>0.05).4.BMI indexThe BMI index was superior in experiment arm after twelfth week of treatment(t=-2.372,P=0.031<0.05),while had no significant difference between three(P>0.05).5.6WMD,pulmonary function,respiratory muscle function and BODE index Intra-group or inter-group,6WMD,pulmonary function,respiratory muscle function and BODE index showed no significant difference between three groups(P>0.05).6,SafetyThe heart rate,blood pressure,respiratory rate,and peripheral blood oxygen saturation monitoring of the three groups were all in a safe range.One patient in the respiratory baduanjin group had mild chest tightness and shortness of breath.After a few minutes of rest,he could relieve himself.There were no adverse reactions in the other 2 group.ConclusionRespiratory Baduanjin may improve the clinical symptoms of patients with severe and extremely severe COPD stability because of CAT scores’ down.As the same time,body weight and BMI index were increased,while there was no significant improvement in active endurance,lung function,and respiratory muscle strength.Breathing baduanjin and lip-abdominal respiration were safe.