Correlation Study Of Dentition Defect And Masticatory Deficiency With Cerebral Small Vessel Disease

ObjectivesTo explore the correlation of dentition defect and masticatory deficiency with cerebral small vessel disease,which provided a research basis for oral health and cerebral small vessel disease,and provided a reference for clinical prevention and treatment of CSVD.MethodsIn the china-japan friendship hospital,from April 2018 to October 2018,a total of119 patients with cerebral small vessel disease who agreed to receive the investigation and study in the department of neurology,meanwhile,119 cases without cerebrovascular disease were examined in the physical examination center,which were selected as the experimental group:1?There were 119 cases in cerebral small vessel disease group and 119 cases in healthy control group.The research objects were received oral examination,and compared with the number of missing tooth,the number of missing posterior tooth,the number of decayed tooth,the number of non-functional biting units and the degree of dentition defect by oral examination.2?Mo CA scale survey was conducted on 90 patients in cerebral small vessel disease group who cooperated with the scale examination,and correlation analysis was conducted between the indexes obtained from oral examination and the scale score.3 ?47 patients who cooperated with TCD examination were tested by a transcranial doppler analyser to detect changes between resting state and after chewing 5 minutes.We analyzed the changes by the end-diastolic peak flow(Vd),systolic peak flow velocity(Vs),mean peak flow velocity(Vm)of middle cerebral artery.4 ? 109 patients with matter lesion were selected from cerebral small vessel disease group as the research objects,we rated the degree of white matter lesion by magnetic resonance imaging(MRI).Correlation analysis was performed between the number of remaining natural teeth and the degree of white matter lesion in the research objects.Results1? In the cerebral small vessel disease group,the number of missing tooth,the number of missing posterior tooth,the number of non-functional biting units,complex dentition defects,the number of missing teeth not repaired,the number of active denture,and the number of fixed + active denture were higher than the healthy control group significantly.In the healthy control group,the number of complete dentition,simple dentition defect and fixed denture were higher than the cerebral small vessel disease group significantly.The state of indexes differ significantly in two group.2? This are significant difference among the number of missing tooth,the number of missing posterior tooth and Mo CA scale score.The Mo CA scale score is greater in group remaining teeth more than 20 than group in remaining teeth less than10 in patients with cerebral small vessel disease significantly.3? After chewing for 5 minutes,the end-diastolic peak flow(Vd),systolic peak flow velocity(Vs),mean peak flow velocity(Vm)of middle cerebral artery in patients with cerebral small vessel disease were all higher than the resting state significantly,and the state of amount of changing differ does not significantly in two sides.4? There is significant correlation between the number of remaining natural tooth and the degree of white matter lesion.Conclusion1?The degree of dentition defect in patients with cerebral small vessel disease was larger than that in normal people,and the recovery degree of mastication function after the defect was smaller than that in normal people.This suggests that there may be a correlation between mastication function lower and cerebral small vessel disease.2? There is a correlation between cognitive impairment,white matter lesion degree and dentition defect degree in patients with cerebral small vessel disease.3?Masticatory exercise can improve the blood flow velocity of the middle cerebral artery in patients with cerebral small vessel disease.