Study Of Relationship Between TCM Constitution,Syndrome Type And Post-stroke Depression In Patients With Lacunar Infarction

Objective: To investigate the relationship between TCM constitution and TCM syndromes in patients with lacunar infarction as well as the relationship between TCM constitution,TCM syndromes,serumUric acid,Total Cholesterol,Triglyceride and Post-stroke Depression(PSD),in order to provide clinical ideas and basis for the prevention and treatment of lacunar infarction and PSD.Methods: 132 patients with lacunar infarction were divided into PSD groups and non-PSD groups.General information was collected,the levels of Uric acid,Total Cholesterol and Triglyceride in fasting serum were observed,TCM constitution types and TCM syndrome types were judged.The test data was analyzed by SPSS 21.0statistical software.Results: Of the 132 patients with lacunar infarction,42 patients had concurrent PSD,accounting for 31.82%.The most common constitution of patients with wind-phlegm-phlegm-stasis syndrome was phlegm dampness,followed by blood stasis,Yin deficiency,Qi deficiency and Yang deficiency,gentle temperament and Qi stagnation,without damp heat.The most common constitution of patients with Qi deficiency and blood stasis syndrome were Qi deficiency,followed by blood stasis,phlegm dampness,Qi depression,gentle temperament and Yang deficiency,Yin deficiency,without damp heat.The most common constitution of patients with Yin deficiency-wind-motion syndrome was Yin deficiency,followed by Qi stagnation,Qi deficiency and phlegm dampness,damp heat,without gentle temperament,blood stasis and Yang deficiency.There were statistically significant differences in the distribution of TCM constitution among patients with the three syndromes.Moreover,there was a strong correlation between constitution and syndrome.The incidence of PSD was higher in patients with Qi stagnation and Yin deficiency,and statistics showed that PSD incidence was related to physical fitness(P < 0.05).The incidence of PSD was higher in patients with wind-phlegm-fire syndrome and Yin deficiency-wind-motionsyndrome,and statistics showed that PSD incidence was not related to physical fitness(P > 0.05).The age,gender and triglyceride level of patients with lacunar infarction were not significantly correlated with the occurrence of PSD(P > 0.05).The serum uric acid and total cholesterol level of patients with lacunar infarction were correlated with the incidence of PSD(P < 0.05),and serum uric acid levels were negatively correlated with depression(r < 0,P < 0.05).Conclusion:There is a close correlation between TCM constitution and syndrome of patients with lacunar infarction.The incidence of PSD in patients with lacunar cerebral infarction is related to TCM constitution,but not related to syndrome.PSD is associated with serum uric acid levels and serum total cholesterol,but not related to serum triglycerides,and the lower the serum uric acid level,the more severe the depression.