| Objective:The purpose of this study is to explore the clinical efficacy of acupuncture combined with Huangqi Janzhongi Decoction Combined with triple therapy in the treatment of peptic ulcer of spleen stomach deficiency cold type,and explore a new way of treatment for peptic ulcer,and improve the treatment level of peptic ulcer.Methods:The subjects were selected from January 2016 to May 2016.The patients with peptic ulcer admitted in our hospital were confirmed to be spleen and stomach deficiency cold type by TCM syndrome differentiation theory.All the 80 cases of peptic ulcer were examined by gastroscopy and met the relevant diagnostic criteria of Chinese and Western medicine.According to different treatment methods,which can be divided into acupuncture and Huangqijianzhong decoction combined with triple therapy treatment group(observation group,40 cases),the classical triple western medicine treatment group(control group,40 cases),more than 2 groups were maintained for 2 weeks,2 weeks after drug withdrawal(after treatment)and gastroscopy clinical observation of treatment than the total efficiency of two groups.After 4 months offollow-up,13C-urea breath test and inspection according to there sults of the 2 groups were compared after Helicobacter pylori eradication rate(Hp eradication rate)and acomparative survey of 2 groups of patients into the treatment group(before treatment)and leave the hospital at different time after drug withdrawal(2weeks,4months)the quality of life score,of the two kinds of treatment in the clinical curative effect after treatment,Hp eradication and the survival rate and quality of nitric oxide in serum before and after treatment (NO),nitric oxide synthase(NOS)differences and incidence ofadverse drug reactions.Results:(1)In the group befor etreatment,the baseline clinical data of 2 patients,such as age,gender,course ofdisease were compared,the difference was not statistically significant(P>0.05);(2)After 2 weeks of discontinuation of statistical clinical treatment of the total efficiency of 2 groups,the observation group(92.50%)was significantly higher than the control group(77.50%),the difference was statistically significant(P<0.05);(3)Check after 4 months of follow-up of 2 groups of patients with Hp eradication rate,the observation group(82.50%)was significantly higher than the control group(65.00%),the difference was statistically significant(P<0.05);(4)Before treatment,the observation group patients quality of life score([90.47±12.83)points] and control group survival quality score[(91.26±14.72)points]nosignificantdifference(P>0.05),stoppingat 2 weeks,4months,patients quality of life scores were observed for[(100.39±20.25)points and(102.47±17.38)points,significantly higher than the controlgroup[(95.27±14.94)points],[(91.29±16.34)points],the difference wasstatistically significant(P<0.05);(5)Before treatment,serum NO[(44.80±9.93)μmol/L],NOS[(22.34±5.43)μmol/L] level and serum NO[(45.27±6.35)μmol/L],NOS[(23.46±7.28)therewasnosignificantdifferenceinmol/L]level(P>0.05);after treatment,the observation group of patients with serum NO[(62.77±12.14)μmol/L],NOS[(30.47±6.69)μmol/L]levelwassignificantly higherthanthatofcontrolthe Goup[(51.03±9.82)μmol/L],[(23.47±7.25)rμmol/L],thedifferencewasstatisticallysignificant(P<0.05);(6)During the treatment period,the incidence of adverse drug reactions in the observation group(5.00%)was significantly lower than that in the controlgroup(12.50%),and the difference was statistically significant(P<0.05).Conclusion:Acupuncturecan promote gastrointestinal peristalsis,reduce gastricacid secretion,protect the gastric mucosa,Huangqijianzhong decoction has the spleenand stomach,cold dispelling.The effect of classical triple therapy can inhibit gastricacid and Helicobacter pylori eradication treatment,three kinds of mutual assistance for the treatment of spleen and stomach deficiency cold type peptic ulcerhas good clinical curative effect,can effectively eradicate Hp and increase serum NO and NOS levels,and it can also reduce the side effects of drugs,is of positive significance to improve the qualityoflifeofpatients. |
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