| Objective: To observe the effect of Fragrant Tianma Decoction on TCM single symptom score,TCM syndrome score,Mantial Office Blood Pressure(MOBP),Home Monitoring Blood Pressure(HBPM),Dynamic Blood Pressure(ABPM)and Blood pressure variability(BPV)in patients of High normal blood pressure(HNBP)with Yin deficiency and Yang hyperactivity,so as to provide an effective prescription for TCM prevention and treatment of HNBP.Methods: A total of 50 cases of HNBP patients with Yin deficiency and Yang hyperactivity who were admitted to the hospital of traditional Chinese medicine of Xinjiang autonomous region from January 2018 to December 2018 and who met the inclusion criteria were collected.They were randomly assigned in a 1:1ratio using a random envelope,and 25 cases in each intervention group and control group.The intervention group give Fragrant Tianma Decoction treatment,while the control group will not be any hypertensive drug intervention.After 6 weeks of intervention,TCM syndrome integral,blood pressure effect and blood pressure variability(BPV)before and after intervention were observed and analyzed statistically.Results:(1)Compared with the control group,TCM single symptom score of headache,dizziness,five upset heat,insomnia,lumbar acid,knee tenderness in the intervention group were lower than the control group,the difference was statistically significant(P<0.05),forgetfulness,palpitation,tinnitus TCM single symptom score were lower than the control group,the difference was not statistically significant(P>0.05);Compared with the control group,the total curative effect of TCM syndromes in the intervention group was better than that in the control group,and the difference was statistically significant(P<0.05).(2)Compared with the control group,MOBP and HBPM of the intervention group were lower than those of the control group,and the difference was statistically significant(P<0.05).Compared with the control group,the intervention group had lower levels of 24 hSBP,NSBP,DSBPand 24 hDBP than the control group,with statistically significant differences(P<0.05),while NDBP and DDBP had no significant changes compared with the control group,with no statistically significant differences(P>0.05).(3)Compared with the control group,BPV of the intervention group showed no significant change compared with that of the control group,and the difference was not statistically significant(P>0.05).Conclusion:(1)Fragrant Tianma Decoction can improve the clinical symptoms of High normal blood pressure patients with Yin deficiency and Yang hyperactivity.(2)Fragrant Tianma Decoctionis is effective in reducing the blood pressure of people with High normal blood pressure of Yin deficiency and Yang hyperactivity.(3)Fragrant Tianma Decoction could not effectively reduce the BPV of High normal blood pressure people of Yin deficiency and Yang hyperactivity.Therefore,Fragrant Tianma Decoction has a certain clinical effect on people of High normal blood pressure of Yin deficiency and Yang hyperactivity. |
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