Perioperative Application Of Shenqi Shoutai Wan In Early Pregnancy Of Transvaginal Reduction Of Fetal Pregnancy

Objective:Through retrospective analysis of clinical data from November 2008 to December 2017 in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Center for reproductive and genetic combination of traditional Chinese and Western medicine of transvaginal multifetal pregnancy reduction in patients with kidney deficiency syndrome of multiple pregnancy,observe the clinical effect and follow-up outcomes(such as pregnancy complications,pregnancy outcome and offspring birth,growth and development).To explore the safety of early pregnancy transvaginal abortion and the value of Shenqi Shoutai Wan in the perioperative period of early multiple pregnancy reduction.Methods:The patients who were admitted from November 2008 to December 2017 and diagnosed as kidney deficiency syndrome of early multiple pregnancy were selected from the hospitalized patient records.All admission records of selected cases,record of course of disease,laboratory tests,medical orders and so on were collected.Choose the information and data from them,such as the age of the patient,the way of pregnancy,the number of fetuses,the number of fetal reduction,the time to reduce the pregnancy time,the symptoms and duration of vaginal bleeding,abdominal pain and waist acid after vaginal reduction,B-ultrasonography before and after operation.According to the follow-up records of reproductive medical record room,multiple pregnancy reduction and follow-up visit,we collected pregnancy complications,delivery weeks,delivery mode,pregnancy outcome,birth weight and neonatal morbidity.The data collected were statistically processed,the data were analyzed,and the conclusions were drawn.Results:1.110 cases of vaginal reduction after operation had less postoperative abdominal pain and waist pain than those before operation,and there was no significant difference in vaginal bleeding days after operation compared with preoperative vaginal bleeding.There was a significant difference in the time between preoperative abdominal pain and postoperative abdominal pain(t=2.148,P=0.034).There was a significant difference between preoperative vaginal bleeding and postoperative vaginal bleeding(t=2.429,P=0.017).There was a significant difference between the 2 groups.There were significant differences in the gestational age of delivery and the epidemiological data in 110 cases of vaginal delivery.The difference between the two groups was statistically significant(t=-2.403,P=0.027).110 cases of transvaginal multifetal pregnancy reduction in single birth group and twin delivery group the average birth weight of newborns and infants with low birth weight rate,birth weight was no significant difference between very low birth(P > 0.05),110 cases of vaginal surgery in patients with impaired fetal pregnancy complication rate was 22.727%,the incidence of neonatal birth 1.744%.2.to 1 fetal group,reduced to 2 mole group,reduced to over 3 fetal delivery mode,the difference was statistically significant(χ2=12.260,P=0.002).Compared to 1 fetal group,reduced to 2,reduced to more than 3 groups of fetal fetal three groups of cervical incompetence incidence,the incidence of OHSS,the difference was statistically significant(P < 0.05).Compared to 1 fetal group,reduced to 2,reduced to more than 3 groups of fetal fetal group three gestational hypertension group,gestational diabetes,premature rupture of membranes,infection,the incidence of anemia in pregnancy rate,the difference was not statistically significant(P > 0.05).Reduced to 1 mole group,reduced to 2,reduced to more than 3 groups of fetal fetal group three age,pregnancy,gestational age,abortion rate,premature delivery rate,average birth weight,low birth weight,birth rate,birth rate of very low birth weight infants,there were no significant differences(P > 0.05).Conclusion:In the early stage of multiple pregnancy,vaginal asthenia during perioperative period,Shenqi Shou Tai pill prolonged the delivery week of twins and increased the quality of double caries after vaginal reduction.The postoperative vaginal bleeding,abdominal pain,and the duration of lumbar acid were reduced,and the postoperative complications were obviously improved.The incidence of complications in pregnancy was reduced and the outcome of the postoperative patients was improved.The outcome of pregnancy reduction to single fetus is better than that of other groups,so it is appropriate to reduce to single fetus by vagina reduction in early pregnancy.There is no increase in the proportion of very low birth weight infants,which can improve the survival rate and improve the development of the newborn,with high safety.