Diagnostic Value Of Serum High Density Lipoprotein Cholesterol For Coronary Artery Disease In Patients With Coronary Heart Disease

Blood lipid as a risk factor for atherosclerotic coronary atherosclerosis,many indicators,such as cholesterol 、 triglyceride 、 high density lipoprotein(HDL-C)、 Low density lipoprotein(LDL-C)and so on,are clinically examined.The aim of this experiment is to compare the indexes of blood lipid test and the sensitivity to the degree of coronary artery disease in patients with coronary heart disease.In particular,the serum high density lipoprotein(HDL-C),as a reversal of atherosclerotic substance,its level and the value of the degree of disease.In order to provide reference for clinical diagnosis.Methods The clinical data of patients with coronary heart disease diagnosed by coronary angiography from December 2012 to December 2017 in our hospital were selected.The severity of coronary artery stenosis was scored by modified Gensini score.According to the median,patients were divided into Observation group(high group)and control group(low group).Analysis of two groups of patient’s serum high-density lipoprotein cholesterol,low density lipoprotein cholesterol and hs-CRP.The receiver operating characteristic curve(ROC)was used to compare the diagnostic efficacy of the above indicators,Pearson correlation test was further used to analyze the correlation between the indicators.Results The level of HDL-C in the observation group was lower than that in the control group(P<0.001).The levels of LDL-C and hs-CRP in the observation group were significantly higher than those in the control group(P< 0.001).ROC curve analysis showed that with 1.292 mmol / L cut-off point,HDL-C predicted the severity of coronary heart disease in observation group was 74.16%,specificity was 69.23%,the area under the curve was 0.790,which was better than LDL-C And hs-CRP.Correlation analysis showed that HDL-C was negatively correlated with LDL-C(r =-0.427,P<0.01)and hs-CRP(r =-0.541,P<0.01)in patients with coronary heart disease.Conclusion Serum high-density lipoprotein cholesterol can predict the severity of coronary heart disease and has a good correlation with LDL-C and hs-CRP,which is superior to the indexes of LDL-C and hs-CRP.