The Research Of Therapying Insomnia Of Non-interaction Between Heart And Kindey With Jiaotai Pill

Objective Insomnia,insomnia is a kind of more colmon diseases in clinical,mainly drug treatment in the clinical treatlent.Compared with western medicine treatment,Chinese medicine treatment has the advantages of high treatment significantly and security.This pill is a kind of based on the theory of traditional Chinese medicine and created by way of drug treatment,in the process of clinical application has more significant effect.As a result,the purpose of this paper is to research this pill treatment heart kidney is not handed over to the clinical cure type insomnia syndromeMethods ① This research takes The First Affiliated Hospial of Wenzhou Medical University in March 2018 to March 2019 treated 126 cases of non-interaction between heart and kindey type insomnia patients as the research object,using the random number table method,the random divided into placebo and this pill treatment group,63 cases in each group.②Materials used in the placebo group with free decoction granules,including sucrose,citric acid,potassium,etc.,made into granules treatment;This pill treatment group adopted this pill for treatment.③Using the Pittsburgh Sleep Quality Index(Pittsburgh Sleep Quality Index,PSQI)points rate of two groups of patients to evaluate the clinical treatment of efficient,and the indicators before and after treatment in patients with two groups of PSQI score and total score.At the same time,using Polysomnography(Polysomnography,PSG)of two groups of patients before and after treatment of sleep and sleep quality evaluation.By High Performance Liquid Chromatography(High Performance Liquid Chromatography,UPLC)in two groups of patients before and after treatment of adenosine level comparison,using enzyme-linked Immunosorbent method(Enzyme-linked Immunosorbent Assay,ELISA)melatonin levels in patients with two groups of comparison.Finally,the two groups after treatment in patients with heart rate,blood pressure,diastolic and systolic blood pressure,weight,blood routine,routine urine and blood biochemical and electrocardiogram(ecg)were observed.Results ①The placebo group effective rate was 82.54%,this pill treatment group effective rate was 96.83%,this pill treatment group higher than in the placebo group(P<0.05).②Governance in the first two groups of patients with the indicators of PSQI score had no statistical difference(P>0.05),there are comparable.After treatment,two groups of patients the PSQI indicators are lower than before treatment(P<0.05).In the FST,ST,SD,DD and total score five indicators,this pill treatment group is lower than the placebo group(P<0.05);In terns of SE,this pill treatment group than placebo group(P<0.05).③Before the treatment,two groups of patients with PSG of sleep and sleep quality there is no statistical differences(P>0.05),there are comparable.After treatment,two groups of patients with PSG two indexes obtained significantly increased(P<0.05).This pill score in treatment group were higher than in the placebo group(P<0.05).④Two groups of patients before treatment of adenosine,and γ-aminobutyric acid and melatonin levels had no statistical difference(P>0.05),there are comparable.After treatment,two groups of patients with adenosine level is lower than before treatment(P>0.05);γ-aminobutyric acid and melatonin levels in two groups of patients were higher than control(P>0.05).In terms of adenosine therapy,this pill levels in treatment group was lower than that of the placebo group(P<0.05).In terms of γ-aminobutyric acid and melatonin levels,the levels of this pill treatment group are higher than the placebo group(P<0.05).⑤After treatment,this pill treatment group were higher than in the placebo group,in terms of heart rate and body weight(P<0.05);This pill for the treatment group blood pressure levels were also significantly lower than that of the placebo group(P<0.05).Two groups of patients with blood routine,routine urine and blood biochemical and electrocardiogram(ecg)were up to the nonnal range,and this pill each index of treatment group were superior to placebo,but there is no statistical difference(P>0.05).Conclusion This pill in improving non-interaction between heart and kindey in the process of the type of insomnia patients,has good clinical effect,can significantly improve the patients’ sleep quality,and has high security,and thus is worthy of clinical application and promotion.