Postoperative Pathology Of Atypical Endometrial Hyperplasia

Objective:To decrease the misdiagnosis rate of endometrial carcinoma in patients with endometrial atypical hyperplasia(EAH)before operation.methods:Retrospective analysis of 69 cases of surgical treatment for atypical hyperplasia of endometrium in the first affiliated hospital of Xinjiang Medical University from 2012 to 2016 according to the pathological results,the cases were divided into Endometrial carcinoma Group(Group A,42 cases)and endometrial atypical hyperplasia Group(Group B,27 cases).Results:Coincidence rate between preoperation and postoperation in diagnosis of EAH was 39.71%(27/69),there was statistically significant difference in age between the two groups(t=2.749,P=0.008),The age distribution of endometrial carcinoma Group was 56.38±8.37,and the age distribution of atypical endometrial hyperplasia group 50.77±8.10.The mean age of patients with endometrial carcinoma was significantly higher than the mean age of patients with EAH diagnosed by postoperation pathological test.there was statistically significant difference in menopause between the two groups(χ~2=5.561,P=0.018).In 42 cases of endometrial carcinoma,23 cases were in menopause,and in 27 cases of atypical hyperplasia,7 cases were in menopause.There were statistically significant differences between the two groups of endometrial(t=2.401,P=0.019).endometrium thickness of endometrial carcinoma Group was 1.33±0.70,endometrial thickness of atypical hyperplasia group was0.96±0.42.Comparing the results of hysteroscopy in two groups,the difference was statistically significant,(χ~2=17.312,P=0.000).In 42 cases of endometrial carcinoma,there were 24 cases of vegetable pattern and polyp,other manifestations were 18 cases,27 cases of atypical hyperplasia of endometrium showed polyp and vegetable pattern,and 2 cases had other manifestations.Conclusion:Age is high risk factor for coexistence with endometrial carcinoma.Attention to age,menopause,Endometrial thickness,Results of hysteroscopy Examination can help to make correct diagnosis and reduce the misdiagnosis rate.