| Objective1.Through reviewing the TCM clinical literature on the treatment of chronic pharyngitis in the past 10 years,the TCM syndrome classification and basic prescriptions were statistically analyzed to clarify the status of traditional Chinese medicine treatment of chronic pharyngitis in recent years.It provided the clinical reference value to pattern differentiation and treatment of TCM in chronic pharyngitis.2.To investigate the characteristics of TCM syndrome distribution of chronic pharyngitis under the instruction of spleen and stomach theory in TCM by applying cluster analysis and factor analysis to the results of clinical cases.Methods1.The clinical research literature on traditional Chinese medicine for treating chronic pharyngitis published in the biomedical database from January 2008 to December 2017 was collected.Extract medical type and prescription,Related databases were established to analyze the characteristics of TCM syndrome distribution.2.The basic information,TCM syndromes,tongue and pulse manifestation and the major clinical symptoms of cases were collected from the spleen specialist clinic.The characteristics of TCM syndrome distribution of chronic pharyngitis under the instruction of spleen and stomach theory in TCM were analyzed by applying frequency analysis,cluster analysis and factor analysis to the data.Results1.The TCM clinical literature on the treatment of chronic pharyngitis in the past 10 years were analyzed and found that the TCM syndromes of chronic pharyngitis were lungkidney yin deficiency and yin deficiency-fire-wang.The selected parties used Yangyin Qingfei Decoction,Liuweidihuang Decoction,Zengye Decoction and Self-made formulas to nourishing yin and clearing pharynx;followed by hernia stagnation,phlegm,lung and spleen qi deficiency,phlegm heat accumulation knot,lung Yu stagnation,qi stagnation and blood stasis,yin deficiency blood stasis,damp heat resistance and liver qi stagnation.The mainly yin deficiency(46.12%),static blood(14.59%),static phlegm(12.54%),qi deficiency(10.53%)and qi stagnation(10.52%).The top 10 clinically used basic prescriptions were Banxiahouputang,Ganluxiaodudan,Huiyanzhuyutang,Yangyinqingfeitang,Liuweidihuangtang,Zengyetang,Sijunzitang,Beimugualousan,Xuefuzhuyutang,Baihegujintang and the others were self-made formulas.2.In 484 cases,there were 286 females(59.09%)which is more than males.The youngest case was 18 and the oldest was 74.The average of age was 37.54±11.80.Most cases were found in spring.Throat discomforts were mainly manifested as pharyngeal foreign body sensation or pinching and mostly appeared to females.TCM syndromes were most common in the spleen and stomach damp-heat followed by liver-stomach disharmony,spleen-stomach weakness,phlegm coagulation and blood stasis,and stomach yin deficiency syndrome.There was a statistically significant difference in the distribution of TCM syndromes between different genders(P<0.05)and the spleen and stomach damp-heat syndrome was dominated by male patients(42.93%).The liver-stomach disharmony syndrome was dominated by female patients(37.76%).The female patients were mostly suffered from phlegm-damp and qi constraint.Besides,phlegm-damp and internal heat were common for the males.190 patients(39.26%)had gastric mucosal lesions confirmed by gastroscopy.Chronic superficial gastritis and peptic ulcer were more common in spleen and stomach damp-heat and reflux esophagitis was mainly based on liver-stomach disharmony.Conclusion1.After sorting and summarizing the documents of the past 10 years,the TCM syndromes of chronic pharyngitis mainly consisted of lung-kidney yin deficiency and yin deficiency resulting in vigorous fire syndrome.Followed by qi stagnation,phlegm,lung spleen qi deficiency,etc.The spleen is the source of phlegm,spleen deficiency is phlegm and endogenous,so the location of chronic pharyngitis is closely related to the spleen and stomach except lung and kidney.2.This disease was found to be closely related to diseases of the digestive system through retrospective analysis of clinical cases.Half of the patients were accompanied by digestive system symptoms.It was found that the spleen-stomach damp heat syndrome was the most common in the Lingnan region,simple yin deficiency syndrome is rare.It is considered to be closely related to the hot and humid climate.Female patients with liverstomach disharmony more common may be due to their emotion was easily to be fluctuated. |
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