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Study On Distribution Characteristics Of Traditional Chinese Medicine Syndromes In Patients With Chronic Atrophic Gastritis And Precancerous Lesions Of Gastric Cancer

Posted on:2018-09-09Degree:MasterType:Thesis
Country:ChinaCandidate:X N PanFull Text:PDF
GTID:2404330515471571Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Objective:This study explores the relationship between precancerous lesions of chronic atrophic gastritis and TCM syndromes,thus providing an objective basis for the prevention and treatment of gastric cancer and better service.Methods:To develop a unified inclusion criteria and exclusion criteria,will meet the standard of 169 patients with chronic atrophic gastritis cases according to TCM four diagnostic data for dialectical classification.The pathologic data of 169 patients were collected and analyzed by SPSS software.The pathological results between the syndromes were compared,and the relationship between pathology and TCM syndromes of precancerous lesions of chronic atrophic gastritis was discussed.Results:1.A total of 169 patients were enrolled in this study,including 94 males and 75 females,with a male to female ratio of 1.3:1.Of which the oldest was 88 years old,the youngest 39 years old,average age 64.50±8.984 years old.Age segment of the four paragraphs,the young elderly(60 years-74 years)for the most,accounting for 59.2%.The history of alcohol and tobacco patients are male-based.2.Chronic atrophic gastritis patients with precancerous lesions in the proportio n of TCM syndromes from high to low order were spleen-stomach-damp-heat sy ndrome(31.4%),syndrome of incoordination between liver and stomach(23.1%),sple en-stomach deficiency syndrome(19.5%),stomach-yin deficiency syndrome(16.6%),s tomach meridian of blood stasis syndrome(9.5%).3.There was significant difference in the distribution of intestinal metaplasia between TCM syndromes and pathologic changes(P<0.05).There were significant differences in the distribution of light,medium and heavy levels of intestinal metaplasia(P<0.01).The distribution of mild and severe intestinal metaplasia was statistically significant(P<0.05).There was no significant difference in the distribution of moderate intestinal metaplasia(P>0.05).Mild more common in the liver and stomach type,moderate more common in the stomach stasis type,severe more common in the stomach Yin deficiency type.4.There were significant differences in the distribution of dysplasia between TCM syndromes and pathological changes(P<0.05).There were significant differences in the distribution of dysplasia between light,medium and heavy(P<0.01).There were significant differences in the distribution of mild and severe dysplasia(P<0.05).There was no significant difference in the distribution of moderate intestinal metaplasia(P>0.05).Mild more common in the spleen and stomach,moderate and severe more common in the stomach stasis type.5.TCM syndromes and pathological changes in the distribution of gastric atrophy were statistically significant(P<0.05).Atrophy in the light,medium and weight of the three different degrees of distribution was statistically significant(P<0.01).Mild and severe atrophy in the distribution of the various syndromes were statistically significant(P<0.05).There was no significant difference in the distribution of moderate syndromes(P>0.05).Mild more common in the liver and stomach type,moderate more common in the stomach stasis type,severe more common in the stomach Yin deficiency type.6.There was no significant difference in the syndrome type and sex and age of TCM patients with chronic atrophic gastritis(P>0.05).There was no significant difference in the distribution of TCM syndromes and HP infection(P>0.05).Conclusions:1.Chronic atrophic gastritis precancerous lesions in patients with traditional Ch inese medicine syndromes are characterized by common spleen and stomach type,liver and stomach type is not followed,stomach stasis blood type is not comm on.2.Chronic atrophic gastritis with precancerous lesions in patients with differe nt pathological types of syndromes are intestinal metaplasia and atrophy to stoma ch and stomach type,stomach-yin deficiency and gastric stasis-based type,dyspla sia to spleen and stomach,stomach Blood stasis type more common.
Keywords/Search Tags:Chronic, atrophic, gastritis, TCM, Syndrome, Precancerous, lesi ons, of, gastric, cancer
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