Analysis On The Related Factors Effect Of Compound Tablet Of Red Sage Root On Acute Cerebral Ischemia Rats Netural Fuction And Angiogenesis

Cerebrovascular accident because of the frequent attacks,the death rate is high,easy to cause the body function and cognitive impairment,cause brain or recurrence of myocardial ischemia,and become the main threat to public health disease,about 80%are ischemic cerebrovascular disease.Although studies have made significant progress,but in terms of applied to clinical,slow progress of concern.This topic experiment using the inspection line of of ischemia rats model,through the ischemia model of rats nerve function score and cerebral ischemia in rats of angiogenic factors effect,to observe the curative effect of compound salvia tablet better exploration of cerebral infarction for clinical drug treatment of new ideas.Select clean level health Sprague wrote Dawley(SD)male rats,weight(200+20 g),a total of 60.Experimental animals raised in hospital room.The whole test process are completed in the laboratory.Separated by the cage,put 6 each cage,maintain indoor temperature between 20 to 25℃,ventilation,indoor relative humidity between 55+/-5%,lighting condition 12 h,12 h,under the condition of dark water is enough,had no effect on feeding,bedding often want to change,normal use 2 days later.(1)normal group(12)every 12 hours once lavage.(2)control(12)only once every 12 hours to fill the stomach.(3)the model control group(12)only once every 12 hours to fill the stomach.(4)thrombosis tong capsule(12)once every 12 hours to fill the stomach.(5)the treatment group(12)only once every 12 hours to fill the stomach.Normal group:this topic experiment using rats in good condition,particularly fast reaction,lively,jiongjiongweishen eyes,diet content increased,the rat Mao Shun slide is thick,fat plump,weight increase.Treatment group and model group:normal rats is generally poor,exercise less,often under the bedding,two eyes malaise,reduce appetite,rat yellow hair dry,rat weight increase or decline is not obvious.Exercise,diet water obviously decrease is more noticeable,balance.Effect can make acute cerebral ischemia of rats obviously improve nerve function,cerebral infarction restoration,can significantly increase bFGF and VEGF in rats,the action of Ang-A and protein expression,at the same time of acute cerebral ischemia rats cerebral ischemia group of collateral cycle have certain improvement effect is established.Conclusion:through the experiment indicated the effect can increase the cerebral ischemia rats infarcts around the expression of vascular growth factors,enhance angiogenesis around infarcts,also can increase the rat nerve function score and other conditions.