The Research On Correlation Of TCM Syndrome Type With Carotid Atherosclerosis With Blood Lipid And Homocysteine

Objective: Testing triglycerides,total cholesterol,low-density lipoprotein,high-density lipoprotein,non-high density lipoprotein,apoB,homocysteine,fasting blood-glucose,glycosylated hemoglobin,BMI,etc.of Hypertension combined with carotid arteriosclerosis to discuss the relationship between different TCM Syndrome types and previous mentioned indicators.Methods:172 patients suffering from hypertension combined with carotid arteriosclerosis in Hypertension Department of Fourth affiliated hospital of Xinjiang Medicine University during September of 2016 and December of2017 were divided into five types as overabundant liver-fire,deficiency of liver-yin and kidney-yin,Qi deficiency and phlegm,blood stasis due to qi deficiency,deficiency of vital energy phlegm-stasis.Detecting triglycerides,total cholesterol,low-density lipoprotein,high-density lipoprotein,fasting blood-glucose,and glycosylated hemoglobin,examining their arteria carotis by b ultrasonic,calculating BMI,WHR,and non-high density lipoprotein in order to make statistical analysis and comparison.Result:(1)There is variance among TG,TC,LDL,HDL,Non-HDL,apoB,Hcy of different TCM type(P<0.05).Moreover,making comparison between any two means in deficiency of vital energy phlegm-stasis,Qi deficiency and phlegm,deficiency of liver-yin and kidney-yin,and overabundant liver-fire group,TC,LDL,apoB of patients in the first group increased remarkably compared with other three groups,which existing statistical significance of variance(P<0.01).Comparing to other groups,Hcy of deficiency of liver-yin and kidney-yin patient showed obvious high data that difference was statistically significant(P<0.01),and no difference between other groups.(2)There is variance among TG,TC,LDL,Non-HDL,apoB,Hcy of different hypertensive combined carotid intimal thickening type(P<0.05).Moreover,making comparison between any two means in deficiency ofvital energy phlegm-stasis,Qi deficiency and phlegm,deficiency of liver-yin and kidney-yin,and overabundant liver-fire group,TC,LDL,Non-HDL,apoB of patients in the first group increased remarkably compared with other three groups,which existing statistical significance of variance(P<0.01).Comparing to other groups,Hcy of deficiency of liver-yin and kidney-yin patient showed obvious high data that difference was statistically significant(P<0.01),and no difference between other groups.(3)Main TCM types of patients suffer from hypertensive combined carotid intimal thickening are overabundant liver-fire and deficiency of liver-yin and kidney-yin.Further,deficiency of vital energy phlegm-stasis,and blood stasis due to qi deficiency are major TCM types for hypertension combined with carotid arteriosclerosis patients.Conclusion:(1)The TC,LDL,and apoB in patients with hypertension and carotid plaque group were significantly higher than those with qi deficiency,liver-kidney yin deficiency,and anger-excessive phlegm.Hcy level in liver and kidney yin deficiency group was significantly higher than other groups.TC,LDL,and Hcy can aggravate carotid atherosclerosis in hypertension.(2)Hypertension combined with carotid atherosclerosis has different levels of physical and chemical indicators at different stages and syndromes.The TC,LDL,non-HDL,apoB in patients with hypertension with carotid intima thickening were significantly higher than those with qi deficiency,liver-kidney yin deficiency,and anger-excessive yang.Hcy in liver and kidney yin deficiency group was significantly higher than that in liver fire and phlegm group.(3)Hypertension combined with carotid artery in different stages of TCM syndrome is gradually evolving.Hypertensive patients with carotid intima thickening mainly present with overabundant liver-fire and deficiency of liver-yin and kidney-yin,meanwhile deficiency of vital energy phlegm-stasis and blood stasis due to qi deficiency mainly exist in hypertensive patients with carotid plaque.