Correlation Analysis Of Vitamin A,D And E Levels With Newly Diagnosed Idiopathic Epilepsy In Children

Objective : To explore the correlation between vitamin A,D,E levels and newly diagnosed idiopathic epilepsy in children.Methods:Sixty-two newly diagnosed idiopathic epilepsy children in the Pediatric Ward and Epilepsy Clinic of the Second Hospital of Dalian Medical University were selected as the study group(epilepsy group).There were 29 cases in the comprehensive attack group and 33 cases in the focal attack group.According to the severity of seizures,there were 7 epileptic state groups,15 frequent cases,and 40 non-sustained or non-frequent groups.Sixty-six healthy children from the physical examination of Dalian Maternal and Child Health Hospital during the same period were selected as the control group.High-performance liquid chromatography(HPLC)was used to determine the serum levels of vitamin A,D and E in children with epilepsy at the onset and the control period respectively.1.Analysis and compare the levels of vitamin A,D,E in 62 children with epilepsy and 76 healthy children.2.The levels of vitamin A,D,E in the 62 children with epilepsy were compared with the types of seizures and the severity of seizures.3.Analysis the changes of vitamin A,D and E in 33 epilepsy children during the onset and control periods.4.Using SPSS 17.0 statistical software for statistical analysis of the experimental data,p <0.05 means the difference was statistically significant.Results:1.The levels of vitamin D and E in children with epilepsy were lower than those in thecontrol group,the difference was statistically significant.Vitamin A levels in children with epilepsy were not statistically significant compared with those in the control group.The detection rate of vitamin E deficiency in children with epilepsy was higher than that in the control group,which was statistically significant.The detection rate of vitamin A and D deficiency in children with epilepsy was statistically insignificant compared with that of the control group2.There was no significant difference in the changes of the levels of vitamin A,D and E in children with epilepsy and seizure type and severity of seizures.3.There was no significant difference in the levels of vitamin A in children with epilepsy in the attack and control periods.4.The level of vitamin D in children with epilepsy was lower than that in children in control group during the onset and control periods,the difference was statistically significant.There was no significant difference in the level of vitamin D during the onset and the control period.5.The level of vitamin E in children with epilepsy at the time of onset was lower than that in control period,the difference was statistically significant.There was no significant difference in the the level of vitamin E in children with epilepsy in control period compared with that in the control group.Conclusions:1.the levers of vitamin D in the newly diagnosed idiopathic epilepsy children were reduced during the onset and control period.2.the levers of vitamin E in the Newly diagnosed idiopathic epilepsy children decreased during the onset,and returned to normal during control period.3.the levers of vitamin A in the new diagnosis of idiopathic epilepsy children during the onset and control period did not change...