Application Of Urinary Calculus Component Analysis And Preventive Guidance

Objective:Through the comparison of blood biochemical tests between patients with upper urinary tract stones and non-lithiasis patients in the same period and the analysis of stone composition in patients with stones,the metabolic abnormal factors and their significance in patients with upper urinary tract calculi were explored.Methods:Selected from the Department of Self-Study from December 1,2016 to December 30,2017,a total of 67 patients with upper urinary tract calculi treated by surgery,of which 59 cases of stone specimens obtained results,29 males and 30 females,aged 25-73 years old,with an average of 50.41±12.5 years old,Among them,there were 10 cases of unilateral renal calculi,3 cases of double kidney stones and 46 cases of unilateral ureteral calculi.Analysis of stone composition using infrared spectrum analyzer.The results were divided into calcium oxalate group and non-Calcium oxalate and 32 patients with no stones in our hospital during the same period were selected as control group,16 males and 16 females.The age ranged from 14 to 68 years,with an average of 43.1 ± 16.8 years.The blood biochemical results of each group were collected in Excel spreadsheets for data analysis.Results:The results suggest that there is no difference in gender and age among the groups.Ninety-three cases of urinary stones containing calcium oxalate in 59 patients accounted for as high as 86.4%,and 3 cases of carbonate apatite,5 cases of uric acid,and 8 cases(13.6%).In the upper urinary tract calculi group,serum creatinine(71.8± 23.5umol/L)and urea nitrogen(6.1 ± 2.0mmol/L)were significantly higher than those of the control group(creatinine 61.1 ± 14.1umol/L,urea nitrogen 5.0 ±1.4mmol/L).)The level of the paired samples t test,P <0.05,the difference was statistically significant.In the calcium oxalate group,serum creatinine(72.5 ±22.8umol/L),urea nitrogen(6.2 ± 1.9mmol/L),non-calcium oxalate group,serum creatinine(76.3 ± 11.5umol/L),and urea nitrogen(6.5 ± 1.1mmol/L).The level was higher than that of the control group(61.1±14.1umol/L)and(5.0±1.4mmol/L).The results suggested that the difference was statistically significant(P<0.05).Comparing the serum calcium,phosphorus,sodium and other electrolyte levels in each group,the difference was not statistically significant.Statistical analysis was performed using the correction formula of the chi-square test.The results suggested that the increase in serum uric acid had significant significance for the formation of uric acid stones(P<0.001).Conclusions:Upper urinary tract stones were mainly composed of calcium oxalate stones,accounting for 86.4%;uric acid stones accounted for 8.5%.Patients with stones have impaired renal function.Lowering blood uric acid is important for preventing the formation of uric acid stones.