The Epidemiological Investigation Of Chronic Kidney Disease In Hunan Province

Objective:To investigate the prevalence and risk factors of chronic kidney disease(CKD)among adults in Hunan Province.Methods:Using cross-sectional study,take the method of multistage sampling,Hunan Province was divided into five regions:east,west,south,north and middle,according to the geographical location of Hunan Province in 2016,Changsha,Zhangjiajie,Yongzhou,Yueyang and Shaoyang were drawn from these five regions,Then take the Maojialong community in Kaifu District,Yongkang Community of Nanzhuangping Street in the Yongding District,Chaoyang Community of Chaoyang Street in the Lingling District,the Central District of Xiangyin County,Chengxi Community of Chengxi Street in the Daxiang District from those cities,and 1200 people were drawn from each of these five communities,6000 adults were selected,and the collected crowds to conduct a questionnaire survey,physical examination and laboratory tests.Results:1.There are 5783 adults with complete data in this survey,including 3331 males and 2452 females.Male:female= 1.36:1,the average age of the total population was(40.28 ± 14.19).Age has no statistical difference between men and women,BMI、SBP、DBP、BUN、SCR、FBG、TC、TG、GFR are significantly different between men and women.2.There were 625 patients with CKD,the prevalence rate was 10.81%.The prevalence rate of CKD in male was 10.32%(344/3331)and that in female was 11.46%(281/2452),There was no significant difference in the prevalence rate of CKD among different sex groups.The prevalence rates of CKD in different age groups were:6.17%(231/3742)、15.61%(217/1390)、24.02%(123/512)、38.85%(54/139),the prevalence rate of CKD increased with the increase of age,and there were significant differences about the prevalence of CKD among different ages.There was no significant difference in the prevalence of CKD in different regions of Hunan Province.Awareness rate of CKD population was 20.8%.The prevalence of CKD 1-5 with CKD was 6.49%、1.68%、2.18%、0.36%、0.07%、0.03%,Most of the CKD patients were in the CKD1 phase.The prevalence of proteinuria,hematuria and reduced eGFR was 1.85%、7.40%、2.65%,they were significant statistical differences between different genders and ages.3.The prevalence rates of hypertension,diabetes mellitus,hyperuricemia,hypertriglyceridemia and hypercholesterolemia in this survey population were:11.19%、4.79%、9.41%、17.07%、15.41%.The prevalence rate of CKD in the patients with chronic diseases mentioned above were:19.01%、21.30%、14.89%、13.48%、14.70%.The prevalence of CKD was significantly different in hypertension subgroup,diabetes subgroup,hyperuricemia subgroup,hypertriglyceridemia subgroup and hypercholesterolemia subgroup.4.Multivariate Logistic regression analysis results:Gender and age were risk factors related to hematuresis.High systolic blood pressure,age and diabetes were risk factors for proteinuria.Age,diabetes and high systolic blood pressure were closely associated with CKD.Conclusions:1.The prevalence of chronic kidney disease in Hunan province was 10.81%,which was simillar to orther area in China.Most of the CKD patients were in the early stage of CKD,and the awareness rate was low.2.Age,diabetes and high systolic blood pressure were the risk factors of CKD in adult population in Hunan province;gender and age were the risk factor of hematuria;high systolic blood pressure,age and diabetes mellitus were the risk factors of proteinuria.